renal proximal tubules

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CHEBI ID

CHEBI:15603 (1)
CHEBI:16010 (1)
CHEBI:16015 (1)
CHEBI:16027 (1)
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CHEBI:16732 (1)
CHEBI:16761 (1)
CHEBI:16856 (1)
CHEBI:16870 (1)
CHEBI:16977 (1)
CHEBI:17053 (1)
CHEBI:17191 (1)
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CHEBI:17345 (1)
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CHEBI:18050 (1)
CHEBI:7916 (1)

Metabolite Name

Cytidine (2)
Guanosine monophosphate (2)
L-Glutamic acid (2)
(+)-ar-Turmerone (1)
(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid (1)
(2R)-5-hydroxy-7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one (1)
(3,4-Dimethoxyphenyl)acetic acid (1)
(9cis)-Retinal (1)
(R)-Equol (1)
(S)-Equol (1)
(S)-Leucic acid (1)
1,4-Dihydro-1-Methyl-4-Oxo-3-Pyridinecarboxamide (1)
1,7-Diphenylhept-4-en-3-one (1)
1-(4-Methoxyphenyl)-2-propanone (1)
1-Aminocyclohexanecarboxylic acid (1)
1-Methyladenosine (1)
1-Methylguanine (1)
1-Methylguanosine (1)
1-Methylhistidine (1)
1-Methylnicotinamide (1)
1-Methyluric acid (1)
1-Methylxanthine (1)
1-Palmitoyl-Sn-Glycero-3-Phosphocholine (1)
10-Nitrolinoleate (1)
10-Undecenoic acid (1)
11-Oxoetiocholanolone (1)
11¦Â-Hydroxyandrosterone (1)
13-HPODE (1)
13-OxoODE (1)
15(S)-HpETE (1)

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Classification

bacteria (1)

Study type

Transcription profiling by array (17)
RNA-seq of coding RNA (4)
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Release Date

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1999 (3)
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2001 (2)
1997 (1)

Lab affiliation

Epithelial Systems Biology Laboratory Systems Biology Center Division of Intramural Research National Heart, Lung and Blood Institute Building 10, Room 6N307 Bethesda, Maryland 20895-1603 (3)
University of Bergen (2)
1. Department of Renal Medicine, Flinders Medical Centre, South Australia, Australia. 2. College of Medicine and Public Health, Flinders University, South Australia, Australia. (1)
Aarhus University Department of Biomedicine Høegh-Guldbergsgade 10 DK-8000 Aarhus C (1)
Biochemistry & Molecular Biology (1)
Center for Kidney Disease, 2nd Affiliated Hospital, Nanjing Medical University, Nanjing, Jiangsu 210003, China (1)
Centre de Recherche du CHU Ste-Justine (1)
Children's Hospital of Nanjing Medical University (1)
Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland (1)
Kidney omics and metabolism Institute of Biomedicine Aarhus University Høegh-Guldbergsgade 10 8000 Aarhus C Denmark (1)
Max-Delbrueck Center, Berlin Institute of Health (BIH), Berlin, Germany (1)
Receptor Biology Lab, University of Antwerp (1)
The Division of Molecular Nephrology, The M.O.E. Key Laboratory of Laboratory Medical Diagnostics, The School of Laboratory Medicine, Chongqing Medical University, Chongqing, People’s Republic of China. (1)

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PPARs and c-Myc regulate metabolism of renal tubules

Different segments of renal tubules have distinct metabolic features and functions, and defective metabolism in renal tubules is involved in the pathobiology of kidney diseases. However, the mechanisms underlying the metabolic regulation in renal tubules remain to be defined. We demonstrated that th...

ORGANISM(S): Mus musculus (Mouse)

2018-11-15 | PXD007828 | Pride

Profiling of Transcripts in Rat Proximal Tubule

Freshly isolated rat kidney proximal tubules were subjected for transcript profiling. Three microarray experiments were done to obtain the kidney proxmial tubule transcriptome.

ORGANISM(S): Rattus norvegicus

2009-01-26 | E-GEOD-13668 | biostudies-arrayexpress

The role of Gusb knockout in renal proximal tubules

PRJNA1478936 | ENA

Gene expression profiles in isolated proximal tubules and whole kidneys of rats after cisplatin-administration

To clarify the effects of cisplatin (cis-diamminedichloroplatinum II, CDDP) on the gene expression profiles in renal proximal tubules, microarray analyses were carried out using total RNA samples isolated from microdissected proximal tubules and whole kidneys. The molecular events underlying acute ...

ORGANISM(S): Rattus norvegicus

2013-12-24 | E-GEOD-37133 | biostudies-arrayexpress

Transcription profiling of mouse Clcn5 knockout in proximal tubules of the kidney

Dent disease has multiple defects attributed to proximal tubule malfunction including low molecular weight proteinuria, aminoaciduria, phosphaturia and glycosuria. In order to understand the changes in kidney function of the Clc5 transporter gene knockout mouse model of Dent disease, we examined gen...

ORGANISM(S): Mus musculus

2008-06-11 | E-GEOD-10162 | biostudies-arrayexpress

The role of Inmt knockout in renal proximal tubules.

PRJNA1232033 | ENA

Multi-omics Analyses Reveal Sex Differences in Mouse Renal Proximal Tubules

PRJNA874593 | ENA

Circadian Gene Expression in Mouse Renal Proximal Tubule

Circadian variability in kidney function has long been recognized but is often ignored as a potential confounding variable in in vivo physiological experiments. To provide a guide for physiological studies on the kidney proximal tubule, we have now created a data resource consisting of expression le...

ORGANISM(S): Mus musculus (Mouse)

2023-04-10 | PXD039006 | Pride

Circadian variation Proteomics Proximal tubule Transcriptomics

Proteomic analysis of renal cancer secretome

Introduction/aim: Renal cell cancer (RCC) is the most frequent kidney malignancy. Here, we aimed to analyze RCC secretome to find key molecules involved in tumor microenvironment regulation. Methods: Conditioned media from five RCC-derived cell lines (Caki-1, KIJ-265T, KIJ-308T, 786-O, and A498) and...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2021-12-02 | MSV000088490 | MassIVE

Isolation and characterization of progenitor-like cells from human renal proximal tubules

The adult kidney has a remarkable capacity for self-renewal upon damage. Whether this regeneration is mediated by dedifferentiating surviving cells or as recently suggested by stem cells has not been unequivocally settled. The stem cell concept is however hampered by lack of consensus regarding the ...

ORGANISM(S): Homo sapiens

2010-11-01 | E-GEOD-23911 | biostudies-arrayexpress

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