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TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity [comparison]
The RIG-I like receptor pathway is stimulated during RNA virus infection by interaction between cytosolic RIG-I and viral RNA structures that contain short hairpin dsRNA and 5M-bM-^@M-^Y triphosphate (5M-bM-^@M-^Yppp) terminal structure. In the present study, an RNA agonist of RIG-I was synthesized ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60572 | biostudies-arrayexpress
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity [Kinetic]
The RIG-I like receptor pathway is stimulated during RNA virus infection by interaction between cytosolic RIG-I and viral RNA structures that contain short hairpin dsRNA and 5M-bM-^@M-^Y triphosphate (5M-bM-^@M-^Yppp) terminal structure. In the present study, an RNA agonist of RIG-I was synthesized ...
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60573 | biostudies-arrayexpress
TranscriptomicsGene expression in IRF3-/- peritoneal macrophage infected with VSV
IRF3 is one of the most critical transcription factor in down stream of pattern recognition receptors (such as toll-like receptor and RIG-I-like receptor) signalling pathway. IRF3 is known to induce the expression of type I IFN gene upon virus infection. To furter examine the role of IRF3 in virus-i...
ORGANISM(S): Mus musculus 
2012-05-19 | E-GEOD-37855 | biostudies-arrayexpress
ProteomicsThe insufficient activation of RIG-I-like signaling pathway in IBRS-2 cells contributes to highly efficient replication of porcine picornaviruses
Seneca Valley Virus (SVV) or commonly known as Senecavirus A (SVA), is one of picornavirus that is associated with vesicular disease and neonatal mortality in swine herds. However, the pathogenesis of SVV remains largely elusive. Our previous study found that SVV replicates extremely faster in porci...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-10-05 | PXD024003 | Pride
Senecavirus a  foot-and-mouth disease virus  rig-i like receptor signaling pathway  interferon  antiviral response 
ProteomicsThe insufficient activation of RIG-I-like signaling pathway in IBRS-2 cells contributes to highly efficient replication of porcine picornaviruses
Seneca Valley Virus (SVV) or commonly known as Senecavirus A (SVA), is one of picornavirus that is associated with vesicular disease and neonatal mortality in swine herds. However, the pathogenesis of SVV remains largely elusive. Our previous study found that SVV replicates extremely faster in porci...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-10-05 | PXD024002 | Pride
Senecavirus a  foot-and-mouth disease virus  rig-i like receptor signaling pathway  interferon  antiviral response 
TranscriptomicsSystems Analysis of a RIG-I Agonist Inducing Broad Spectrum Inhibition of Virus Infectivity
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-08-21 | E-GEOD-60574 | biostudies-arrayexpress
UnknownRIG012 assists in the treatment of pneumonia by inhibiting the RIG-I-like receptor signaling pathway.
Not available
S-EPMC11563779 | biostudies-literature
UnknownN4BP3 Regulates RIG-I-Like Receptor Antiviral Signaling Positively by Targeting Mitochondrial Antiviral Signaling Protein.
Not available
S-EPMC8646042 | biostudies-literature
UnknownCancer therapies activate RIG-I-like receptor pathway through endogenous non-coding RNAs.
Not available
S-EPMC5041995 | biostudies-literature
UnknownUiO-66 nanoparticles combat influenza A virus in mice by activating the RIG-I-like receptor signaling pathway.
Not available
S-EPMC10925002 | biostudies-literature
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