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ProteomicsSynergistic effects between rutin and ascorbic acid in the protection of the proteome of 3D-cultured human skin fibroblasts from UVA radiation
This study demonstrates the cooperation of rutin and ascorbic acid in cytoprotective action against UVA induced changes in the context of proteins involved in gene expression, catalytic processes, antioxidant pathways, as well as signalling molecules including transmembrane channels. The main advant...
ORGANISM(S): Homo sapiens (Human) 
2020-11-20 | PXD018730 | Pride
Skin fibroblasts  uva radiation  rutin  ascorbic acid  proteomics  3d cell culture 
GenomicsEx vivo human gut microbial degradation of rutin and genistein
Ex vivo human gut microbial degradation of rutin and genistein
PRJEB76448 | ENA
ProteomicsSynergistic Therapeutic Effects of D-Mannitol-Cerium-Quercetin (Rutin) Coordination Polymer Nanoparticles on Acute Lung Injury
In our latest study, we pioneered the use of D-Mannitol-Cerium-Quercetin/Rutin coordination polymer nanoparticles (MCQ/R NPs) as a potential remedy for ALI. our in vivo studies with LPS-induced ALI mice showed significant mitigation of lung tissue inflammation. This groundbreaking research presents ...
ORGANISM(S): Mus Musculus 
2024-04-10 | PXD051350 |
TranscriptomicsRutin ameliorates stress-induced blood‒brain barrier dysfunction and cognitive decline via the endothelial HDAC1‒Claudin-5 axis
Background: Emerging evidence suggests that chronic stress compromises blood‒brain barrier (BBB) integrity by disrupting brain microvascular endothelial cells (BMECs), contributing to the development of cognitive impairments. Thus, targeting the BBB is expected to be a promising treatment strategy. ...
ORGANISM(S): Homo sapiens 
2025-04-09 | GSE288810 | GEO
GenomicsTranscriptomic profiling of senescent human stromal cells upon medicinal intervention with rutin
Transcriptomic profiling of senescent human stromal cells upon medicinal intervention with rutin
PRJNA786575 | ENA
TranscriptomicsTranscriptomic profiling of senescent human stromal cells upon medicinal intervention with rutin
Aging and age-related pathologies can be delayed by specifically targeting the senescence-associated secretory phenotype (SASP), a hallmark feature of senescent cells. Achieving the goal using natural or synthetic agents would have a tremendous impact on the quality of lifespan and burden of age-rel...
ORGANISM(S): Homo sapiens 
2023-11-02 | GSE190279 | GEO
GenomicsRutin ameliorates stress-induced blood‒brain barrier dysfunction and cognitive decline via the endothelial HDAC1‒Claudin-5 axis
Rutin ameliorates stress-induced blood‒brain barrier dysfunction and cognitive decline via the endothelial HDAC1‒Claudin-5 axis
PRJNA1219537 | ENA
TranscriptomicsTranscription profiling of mouse mdr1a-/- a model of IBD response to dietary curcumin and rutin on colonic inflammation
Damage of the intestinal epithelial barrier by xenobiotics or reactive oxygen species and a dysregulated immune response are both factors involved in the pathogenesis of inflammatory bowel diseases (IBD). Curcumin and rutin are polyphenolic compounds known to have anti-oxidant and anti-inflammatory ...
ORGANISM(S): Mus musculus 
2008-06-11 | E-GEOD-10684 | biostudies-arrayexpress
TranscriptomicsEffects of dietary curcumin and rutin on colonic inflammation and gene expression in mdr1a-/- mice, a model of IBD
Damage of the intestinal epithelial barrier by xenobiotics or reactive oxygen species and a dysregulated immune response are both factors involved in the pathogenesis of inflammatory bowel diseases (IBD). Curcumin and rutin are polyphenolic compounds known to have anti-oxidant and anti-inflammatory ...
ORGANISM(S): Mus musculus 
2008-04-10 | GSE10684 | GEO
GenomicsTranscriptional alteration by alpha-glucosyl-rutin in human fibroblasts, iPSCs, and keratinocytes.
Transcriptional alteration by alpha-glucosyl-rutin in human fibroblasts, iPSCs, and keratinocytes.
PRJNA695211 | ENA
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