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ProteomicsUltra-deep human phosphoproteome reveals different regulatory nature of Tyr and Ser/Thr-based signaling
Regulatory protein phosphorylation controls nearly every normal and pathophysiological signaling system in eukaryotic cells. Despite great advances in mass spectrometry based-proteomics, the total number, localization and site-specific stoichiometry of this post-translational modification (PTM) are ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080701 | MassIVE
ModelsHuarat2016 -Starvation-induced Ser/Thr protein kinase ArnS (Saci_1181) (Model 14)
Huarat2016 -Starvation-induced Ser/Thr protein kinase ArnS (Saci_1181) (Model 14) This model is described in the article: ArnS, a kinase involved in starvation-induced archaellum expression. Haurat MF, Figueiredo AS, Hoffmann L, Li L, Herr K, J Wilson A, Beeby M, Schaber J, Albe...
2016-12-05 | MODEL1607210000 | BioModels
ProteomicsE. coli toxin YjjJ (HipH) is a Ser/Thr protein kinase that impacts cell division, carbon metabolism and ribosome assembly
Protein Ser/Thr kinases are post-translational regulators of key molecular processes in bacteria, such as cell division and antibiotic tolerance. Here we characterize the E. coli toxin YjjJ (HipH), a putative protein kinase annotated as a member of the family of HipA-like Ser/Thr kinases which are i...
ORGANISM(S): Escherichia coli 
2022-11-28 | PXD033071 | Pride
Escherichia coli Toxin yjjj Kinases 
ProteomicsThe Ser/Thr Protein Kinase Protein-Protein Interaction Map of M. tuberculosis
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis, the leading cause of death among all infectious diseases. There are 11 eukaryotic-like serine/threonine protein kinases (STPKs) in Mtb, which are thought to play pivotal roles in cell growth, signal transduction and pathogenesi...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2017-06-06 | PXD006389 | Pride
Protein-protein interaction Cell wall Murc Ser/thr protein kinase 
ProteomicsImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosaImpacts of Ser/Thr protein kinase Stk1 on proteome, twitching motility and competitive advantage in Pseudomonas aeruginosa
Pseudomonas aeruginosa is a ubiquitous Gram-negative bacterium in the environment and a leading cause of nosocomial infections worldwide. Therefore, it is listed by the World Health Organization as one of the human pathogens that urgently need to develop new antibacterial drugs. Recent findings have...
ORGANISM(S): Pseudomonas aeruginosa PAK 
2021-07-07 | PXD027148 | Pride
Stk1 Ser/thr protein kinase Twitching motility Competitive advantage Pseudomonas aeruginosa. Proteome 
GenomicsSystems biology of S.aureus adaptation under Ser/Thr kinase wild type and mutations of kinase (pknB) or phosphatase (stp)
Systems biology of S.aureus adaptation under Ser/Thr kinase wild type and mutations of kinase (pknB) or phosphatase (stp)
PRJNA504786 | ENA
TranscriptomicsSystems biology of S.aureus adaptation under Ser/Thr kinase wild type and mutations of kinase (pknB) or phosphatase (stp)
Different transcriptome, metabolome, and phosphoproteome studies have already indicated a regulatory role of Ser/Thr phosphorylation in the central metabolism of S. aureus. However, it remains still unknown how this exactly tunes its metabolism. For that reason, Extreme Pathway Analysis was used to ...
ORGANISM(S): Staphylococcus aureus Staphylococcus aureus subsp. aureus str. Newman 
2019-11-11 | GSE122362 | GEO
UnknownCellular Ser/Thr-kinase assays using generic peptide substrates.
Not available
S-EPMC2774688 | biostudies-literature
ProteomicsThe GATOR2–mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation
Sestrins represent a family of stress-inducible proteins that prevent the progression of many age- and obesity-associated disorders. Endogenous Sestrins maintain insulin-dependent AKT Ser/Thr kinase (AKT) activation during high-fat diet (HFD)-induced obesity, and overexpressed Sestrins activate AKT ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-15 | PXD015824 | Pride
Sestrin2 Akt pkb Liver metabolism Gator2 Mtor 
MetabolomicsMetabolic effects of the protein kinase R
Not available
ORGANISM(S): Mus musculus 
ST002412 | MetabolomicsWorkbench
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