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ProteomicsLong Non-coding RNA SNHG1 in Neuroblastoma
Neuroblastoma (NB) is an embryonal tumor with various clinical presentations and behaviors. Several genomic alterations has been well-studied in NB, among which genomic amplification of MYCN oncogene, is a strong prognostic biomarker with worsens outcome. Long noncoding RNAs (lncRNAs), constitute ma...
ORGANISM(S): Homo sapiens (Human) 
2022-03-01 | PXD007121 | Pride
Neuroblastoma  mycn  long non-coding rna  snhg1  rna-protein pull down assay  lc-ms/ms  rna-immunoprecipation (ip)   matr3 
GenomicsThe Long Noncoding RNA SNHG1 Regulates both the Local and Distal Genes in Cancer
lncRNAs play important roles in various physiological and pathological processes. However, the detailed molecular mechanisms by which lncRNAs act are still incomplete. Here, we functionally characterized the nuclear-enriched lncRNA SNHG1 which is highly expressed in several types of cancer relative ...
ORGANISM(S): Homo sapiens 
2016-08-20 | E-GEOD-85842 | biostudies-arrayexpress
GenomicsInvestigation of SNHG1 functions in neuroblastoma
Investigation of SNHG1 functions in neuroblastoma
PRJNA485246 | ENA
GenomicsThe long noncoding RNA SNHG1 promotes carboplatin resistance retinoblastoma
The long noncoding RNA SNHG1 promotes carboplatin resistance retinoblastoma
PRJNA719721 | ENA
GenomicsChromatin status under knock-down of SNHG1 in neuroblastoma [ChIP-seq]
Chromatin status under knock-down of SNHG1 in neuroblastoma [ChIP-seq]
PRJNA837442 | ENA
GenomicsChromatin status under knock-down of SNHG1 in neuroblastoma [ATAC-seq]
Chromatin status under knock-down of SNHG1 in neuroblastoma [ATAC-seq]
PRJNA837443 | ENA
TranscriptomicsOverexpression Studies of SNHG1 Revealed that SNHG1 Regulated the Distal Genes Expression in Cancer
Many long noncoding transcripts are involved in cancer progression. Here, we utilized high-throughput microarray to compare the transcriptome alterations between the SNHG1 overexpression or control in HCT116 cell lines. Two isoforms of SNHG1 (denoted as SNHG1S and SNHG1L in the present work) were se...
ORGANISM(S): Homo sapiens 
2015-10-01 | GSE69888 | GEO
TranscriptomicsInvestigation of SNHG1 functions in neuroblastoma
The gene expression profiles of SK-N-BE(2)C cell lines with CRISPR/Cas9-mediated depletion of SNHG1 were perfomed to investigate the role of SNHG1 in neuroblastoma
ORGANISM(S): Homo sapiens 
2021-08-01 | GSE118333 | GEO
GenomicsRole of SNHG1 on the polarization of macrophages and inflammation in RAW264.7 cells
Role of SNHG1 on the polarization of macrophages and inflammation in RAW264.7 cells
PRJNA786339 | ENA
GenomicsChromatin status under knock-down of SNHG1 in neuroblastoma [ChIP-seq]
The small nucleolar RNA host gene 1 (SNHG1) is a novel oncogenic long non-coding RNA (lncRNA) aberrantly expressed in different tumor types. We previously found highly expressed SNHG1 was associated with poor prognosis and MYCN status in neuroblastoma (NB). However, the molecular mechanisms of SNHG1...
ORGANISM(S): Homo sapiens 
2022-09-27 | GSE202829 | GEO
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