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MetabolomicsSpatiotemporal determination of metabolite activities in the corneal epithelium on a chip
The corneal epithelial barrier maintains the metabolic activities of the ocular surface by regulating membrane transporters and metabolic enzymes responsible for the homeostasis of the eye as well as the pharmacokinetic behavior of drugs. Despite its importance, no established biomimetic in vitro me...
2021-07-13 | MTBLS2274 | MetaboLights
MetabolomicsSingle-cell Transcriptomics and Time-series Metabolite Profiling Reveal the Spatiotemporal Regulation of Flavonoid Biosynthesis Genes and Phytohormone Homeostasis by PAP1 in Arabidopsis
Understanding the spatiotemporal regulation of specialized metabolism in plants is critical for advancing both basic plant biology and biotechnological applications. In this study, we utilized single-cell RNA sequencing (scRNA-seq) and time-series metabolite profiling to investigate the regulation o...
2025-05-27 | MTBLS12459 | MetaboLights
ProteomicsGSG1L-containing AMPA receptors are complexes with unique spatiotemporal expression, subunit composition and gating properties
Transmembrane AMPA receptor regulatory proteins (TARPs) and germ cell-specific gene 1-like protein (GSG1L) are claudin-type AMPA receptor (AMPAR) auxiliary subunits that profoundly regulate glutamatergic synapse strength and plasticity. While AMPAR-TARP complexes have been extensively studied, less ...
ORGANISM(S): Rattus norvegicus (Rat) 
2024-01-26 | PXD044621 | Pride
Lc-ms/ms Interactomics 
UnknownThe spatiotemporal expression pattern of Syndecans in murine embryonic teeth.
Not available
S-EPMC7293924 | biostudies-literature
GenomicsSpatiotemporal proteomics reveals dynamic antiparallel gradients shaping signalling waves [Spatiotemporal RNAseq]
Spatiotemporal proteomics reveals dynamic antiparallel gradients shaping signalling waves [Spatiotemporal RNAseq]
PRJNA1299794 | ENA
GenomicsA spatiotemporal organ-wide gene expression and cell atlas of the developing human heart
The process of cardiac morphogenesis in humans is incompletely understood. Its full characterization requires a deep exploration of the organ-wide orchestration of gene expression with a single-cell spatial resolution. Here, we present a molecular approach that reveals the comprehensive transcriptio...
EGAS00001003996 | EGA
GenomicsSpatiotemporal Patterns of Gene Expression Around Implanted Silicon Electrode Arrays
Spatiotemporal Patterns of Gene Expression Around Implanted Silicon Electrode Arrays
PRJNA1070633 | ENA
GenomicsSpatiotemporal Transcriptome of the Human Brain

Comprehensive knowledge about the spatiotemporal dynamics of the brain transcriptome is essential for a better understanding of neurodevelopment, sexual dimorphism, and evolution, as well as our increased susceptibility to certain brain disorders. We generated and analyzed genome-wide exo...

phs000406.v1.p1 | EGA
GenomicsSpatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration
Spatiotemporal expression of HMGB2 regulates cell proliferation and hepatocyte size during liver regeneration
PRJNA822301 | ENA
TranscriptomicsSpatiotemporal brassinosteroid signaling and antagonism with auxin control Arabidopsis root growth.
Analysis of brassinosteroid (BR) and auxin effects on gene expression in Arabidopsis roots. Our genomic results indicate that BR and auxin induce largely opposite gene expression responses in primary roots. RNA-Seq for 7-day-old Arabidopsis Col-0, dwf4, bri1-116, and bri1-116;bzr1-1D roots grown on ...
ORGANISM(S): Arabidopsis thaliana 
2015-04-30 | E-GEOD-52966 | biostudies-arrayexpress
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