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Regulation of brain aging by neutral sphingomyelinase 2
We sequenced mRNA from three independent pairs of mock and c-SRC transformed mouse embryonic fibroblasts and examined changes in expression of sphingolipid metabolism genes Three independent cultures of NIH3T3 MEFs were retrovirally transduced with either pBabe-Puro, og pBabe-Puro containing c-srcY5...
ORGANISM(S): Mus musculus 
Genome-wide maps of gene expression in alkaline sphingomyelinase knockout mice
Acid sphingomyelinase (ASM) inhibitors, which are clinically used as anti-depressants for ~60 years, have recently been shown to enhance stroke recovery in rodents. Using mice and cerebral microvascular endothelial cells exposed to ischemia/reperfusion (I/R) we show that the antidepressants amitript...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD024106 | Pride
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