stable isotope dimethyl-labeled proteomics

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Biomolecular Mass Spectrometry and Proteomics Group, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, 3584 CH Utrecht, The Netherlands; Netherlands Proteomics Centre and Cancer Genomics Centre, 3584 CH Utrecht, The Netherlands; Mass Spectrometry/Proteomics Facility, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands. (1)
Biomolecular Mass Spectrometry and Proteomics Utrecht University The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Science, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands; Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, the Netherlands. Netherlands Proteomics Centre, Padualaan 8, 3584 CH Utrecht, the Netherlands (1)
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Center for Integrated Protein Science at the Department of Chemistry, Technische Universität München, Garching b. München 85747, Germany; Chair of Organic Chemistry II, Technische Universität München, Garching b. München 85747, Germany (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)
Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany. (1)
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Department of Molecular Medicine and Neurodegeneration New Medicines Center, The Scripps Research Institute, La Jolla, CA 92037, USA (1)
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Department of Physiology and Department of Neurobiology. David Geffen School of Medicine, University of California Los Angeles. Los Angeles, CA 90095-1751, USA (1)
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Division of Biotechnology,Dalian Institute of Chemical Physics,Chinese Academy of Sciences (1)
European Molecular Biology Laboratory, Genome Biology Unit Meyerhofstr. 1 69117 Heidelberg Germany (1)
Food Allergy Research and Resource Program, Department of Food Science and Technology, University of Nebraska-Lincoln (1)

Modification

4x(2)H labeled dimethylated residue (2)
N6-dimethyl-L-lysine (2)
4x(2)H labeled dimethylated L-lysine (1)
6x(2)H labeled dimethylated L-arginine (1)

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Comparing SILAC- and stable isotope dimethyl-labeling approaches for quantitative proteomics.

Comparison of SILAC and reductive dimethyl labeling; also applied both methods to affinity enrichment experiments with and without fractionation.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2018-08-29 | MSV000082868 | MassIVE

Minimal deuterium isotope effects in quantitation of dimethyl-labeled complex proteomes analyzed with capillary zone electrophoresis/mass spectrometry.

Not available

S-EPMC7540333 | biostudies-literature

Discovery of peptide biomarkers in male Eupolyphaga sinensis Walker (Tubiechong) by dimethyl labeling-based quantitative peptidomics analysis

Eupolyphaga sinensis Walker is a traditional Chinese medicinal insect. However, the peptide composition differences between male and female ES, which may underlie their distinct medicinal efficacies, remain largely unexplored. In this study, we performed a quantitative peptidomics analysis using sta...

ORGANISM(S): Eupolyphaga sinensis

2026-09-07 | PXD080333 | Pride

In-depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immunoaffinity purification and stable isotope dimethyl labeling.

Not available

S-EPMC2808269 | biostudies-literature

Feasibility of Utilizing Stable-Isotope Dimethyl Labeling in Liquid Chromatography⁻Tandem Mass Spectrometry-Based Determination for Food Allergens-Case of Kiwifruit.

Not available

S-EPMC6571768 | biostudies-literature

SPECHT - single-stage phosphopeptide enrichment and stable-isotope chemical tagging: quantitative phosphoproteomics of insulin action in muscle.

Not available

S-EPMC4289458 | biostudies-literature

Mass Defect-Based N,N-Dimethyl Leucine Labels for Quantitative Proteomics and Amine Metabolomics of Pancreatic Cancer Cells.

Not available

S-EPMC5338727 | biostudies-literature

Combining Data Independent Acquisition With Spike-In SILAC (DIA-SiS) Improves Proteome Coverage and Quantification.

Not available

S-EPMC11795695 | biostudies-literature

Isotope Tracing of Macrophage Efferocytosis-Derived Fatty Acids into Histone Acetylation in Tumor Cells

This dataset presents a mass spectrometry-based proteomic analysis of histone acetylation in tumor cells influenced by macrophage efferocytosis. Through stable isotope tracing with [U-13C] palmitate, we mapped the incorporation of macrophage efferocytosis-derived carbon into histone acetylation in t...

ORGANISM(S): Homo sapiens (Human)

2026-04-27 | PXD062191 | Pride

Histone acetylation Hepatocellular carcinoma Epigenetic Lc-ms/ms

Na2CO3-responsive phosphoproteins in chloroplasts from Puccinellia tenuiflora leaves

Alkali-salinity exerts severe osmotic, ionic, and high-pH stresses to plants. Photosynthetic machinery is especially sensitive to saline-alkali stress. In addition, reversible protein phosphorylation also play crucial roles in plant salt resistance. While our knowledge on protein phosphorylation eve...

ORGANISM(S): Oryza sativa (Rice)

2021-08-30 | PXD005472 | Pride

Na2co3 Phosphoproteomics Chloroplast Puccinellia tenuiflora

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