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TranscriptomicsDormancy within Staphylococcus epidermidis biofilms: a transcriptomic analysis by RNA-seq
We sequenced mRNA from three independent biological replicates of Staphylococcus epidermidis biofilms with different proportion of dormant cells. Whole trancriptome analysis of Staphylococcus epidermidis biofilms with prevented and induced dormancy.
ORGANISM(S): Staphylococcus epidermidis 
2014-08-28 | E-GEOD-60834 | biostudies-arrayexpress
TranscriptomicsAI-2-dependent gene regulation in Staphylococcus epidermidis
Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling molecule, but in many bacteria AI-2 control of gene expression is not completely understood. ...
ORGANISM(S): Staphylococcus epidermidis 
2008-10-10 | E-GEOD-9427 | biostudies-arrayexpress
MetabolomicsSkin-to-blood pH shift triggers metabolome and proteome global remodelling in Staphylococcus epidermidis
Not available
ORGANISM(S): Staphylococcus epidermidis 
ST002277 | MetabolomicsWorkbench
TranscriptomicsSarZ is a key regulator of biofilm formation and virulence in Staphylococcus epidermidis
Biofilm-associated infection by the leading nosocomial pathogen Staphylococcus epidermidis is a major problem for the public health system. Here we used an especially discriminatory, two-step screen to discover key biofilm factors. We identified the transcriptional regulator and SarA paralog SarZ as...
ORGANISM(S): Staphylococcus epidermidis 
2010-05-25 | E-GEOD-8523 | biostudies-arrayexpress
TranscriptomicsStaphylococcus epidermidis biofilms transcriptome alterations upon incubation with whole human blood
The ability of S. epidermidis to withstand the high bactericidal activity of the hostM-bM-^@M-^Ys blood is crucial for its systemic dissemination. Hence, in order to identify genes and pathways involved in the bacteriumM-bM-^@M-^Ys survival in human blood, we have characterized the transcriptome of ...
ORGANISM(S): Staphylococcus epidermidis 
2014-08-29 | E-GEOD-52111 | biostudies-arrayexpress
TranscriptomicsRegulatory role of SrrAB two-component system in Staphylococcus epidermidis growth and biofilm formation
Biofilm formation is considered the most important factor involved in pathogenicity of Staphylococcus epidermidis.We investigated the role of two-component signal transduction system (TCS) srrAB, which was up-regulated under micro-aerobic condition, in the growth and biofilm formation of S. epidermi...
ORGANISM(S): Staphylococcus epidermidis 
2014-11-21 | E-GEOD-47101 | biostudies-arrayexpress
ProteomicsComprehensive Succinylome Profiling Reveals the Pivotal Role of Lysine Succinylation in Energy Metabolism and Quorum Sensing of Staphylococcus epidermidis
Background: Lysine succinylation is a newly identified PTM, which exists widely from prokaryotes to eukaryotes and participates in various cellular processes, especially in the metabolic processes. Staphylococcus epidermidis is a commensal bacterium in the skin, which attracts more attention as a pa...
ORGANISM(S): Staphylococcus epidermidis 
2021-02-25 | PXD022866 | Pride
Post-translational modification  lysine succinylation  staphylococcus epidermidis  energy metabolism  succinyltransferase  desuccinylase  quorum sensing 
TranscriptomicsStaphylococcus aureus and Staphylococcus epidermidis transcriptomic response to sapienic acid
Staphylococcus aureus Newman and Staphylococcus epidermidis Tu3298, 20 minutes post challenge with sub-inhibitory concentration of sapienic acid vs equivalent concentration of ethanol. Challenge was added at mid logarithmic growth (OD600 0.5). Biological triplicates of samples were sequenced.
ORGANISM(S): Staphylococcus epidermidis 
2016-07-31 | E-MTAB-4587 | biostudies-arrayexpress
ProteomicsRevelation of AbfR in Regulation of Mismatch Repair and Energy Metabolism in S. epidermidis by Integrated Proteomic and Metabolomic Analysis
Staphylococcus epidermidis is a common causative of nosocomial infections associated with indwelling medical devices. To date, the mechanisms of the pathogenicity and drug resistance of S. epidermidis have not been clearly elucidated. AbfR has been previously identified as an oxidation-sensing regul...
ORGANISM(S): Staphylococcus epidermidis RP62A Bacteria 
2020-07-29 | PXD020096 | Pride
Tmt10-plex labelling Staphylococcus epidermidis 
TranscriptomicsTranscriptomic analyses of Staphylococcus epidermidis in mixed-species biofilms with Candida albicans
To explain enhanced biofilm formation and increased dissemination of S. epidermidis in mixed-species biofilms, microarrays were used to explore differential gene expression of S. epidermidis in mixed-species biofilms. One sample from single species biofilm (S1) and mixed-species biofilm (SC2) were e...
ORGANISM(S): Candida albicans 
2012-02-28 | E-GEOD-35438 | biostudies-arrayexpress
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