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MetabolomicsDivergent relationships between faecal microbiota and metabolome following distinct antibiotic-induced disruptions
The intestinal microbiome plays an essential role in regulating many aspects of host physiology, and its disruption through antibiotic exposure has been implicated in the development of a range of serious pathologies. The complex metabolic relationships that exist between members of the intestinal m...
2017-03-03 | MTBLS422 | MetaboLights
MetabolomicsMulti-hierarchical profiling the structure-activity relationships of engineered nanomaterials at nano-bio interfaces
Increasing concerns over the possible risks of nanotechnology necessitates breakthroughs in structure-activity relationship (SAR) analyses of engineered nanomaterials (ENMs) at nano-bio interfaces. However, current nano-SARs are often based on univariate assessments and fail to provide tiered views ...
2020-01-23 | MTBLS721 | MetaboLights
ProteomicsStructure-function Relationships in Human Tendons: Interfascicular Matrix Specialisation in the Achilles Tendon C4PR_LIV
Tendon is a highly aligned connective tissue, in which the macro-structure consists of collagen-rich fascicles surrounded by interfascicular matrix (IFM). In a series of recent studies in equine tissue, we have demonstrated specialisation of tendon composition, structure and mechanics to achieve the...
ORGANISM(S): Homo sapiens (Human) 
2020-11-11 | PXD018212 | Pride
Structure-function Fascicles  interfascicularmatrix  mechanical testing  mass spectrometry  ageing 
UnknownCorrection to: Multi-scale account of the network structure of macaque visual cortex.
Not available
S-EPMC7645579 | biostudies-literature
UnknownMulti-scale account of the network structure of macaque visual cortex.
Not available
S-EPMC5869897 | biostudies-literature
ProteomicsStructure–Function Relationships and Therapeutic Potential of Non-Covalent PPARγ Inverse Agonists
Peroxisome proliferator-activated receptor gamma (PPARγ) is a validated therapeutic target for type 2 diabetes (T2D), but current FDA-approved agonists such as the glitazones are limited by adverse effects. SR10171, a non-covalent partial inverse agonist with modest binding potency, improves insulin...
ORGANISM(S): Homo sapiens (Human) 
2025-11-15 | PXD066095 | Pride
UnknownAxonal structure-function relationships across experimental modalities.
Not available
S-EPMC12723409 | biostudies-literature
UnknownStructure-function relationship of working memory activity with hippocampal and prefrontal cortex volumes.
Not available
S-EPMC3858000 | biostudies-literature
UnknownBrain structure-function associations identified in large-scale neuroimaging data.
Not available
S-EPMC5102954 | biostudies-literature
UnknownMesoscale structure-function relationships in mitochondrial transcriptional condensates.
Not available
S-EPMC9565167 | biostudies-literature
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