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TranscriptomicsTranscription profiling of Arabidopsis tocopherol deficient seedlings
Tocopherols (Vitamin E) are lipophilic antioxidants that are synthesized by all plants and are particularly abundant in seeds. Two tocopherol deficient mutant loci were used to examine how tocopherol deficiency impacts global gene expression during the critical peroid of germination and early seedl...
ORGANISM(S): Arabidopsis thaliana 
2009-04-10 | E-GEOD-4847 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of chicken liver after alpha- and gamma-tocopherol supplementation in case of increased oxidative stress susceptibility
A 30-day nutritional trial in broiler chickens (Ross 308) was conducted to investigate how specific forms of vitamin E (α- and γ-tocopherol) and their combination impact liver gene expression when oxidative susceptibility of the organism is induced by high n-3 polyunsaturated fatty acids (PUFA) in...
ORGANISM(S): Gallus gallus 
2017-02-28 | E-MTAB-4507 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse brain to identify age-related transcriptional changes and the effect of dietary supplementation of vitamin E
We established the transcriptional profile of brain aging and examine the global effects of vitamin E supplementation on age-related alterations in expression in the aged mouse brain. Experiment Overall Design: Gene expression profiles were obtained from the neocortex tissues of 5-month-old controls...
ORGANISM(S): Mus musculus 
2009-09-23 | E-GEOD-8150 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse heart after dietary supplementation of vitamin E in the mouse heart to investigate age-related transcriptional changes
To investigate the global effects of vitamin E supplementation on heart aging, we used high-density oligonucleotide arrays to measure transcriptional alterations in 30-month-old B6C3F1 mice supplemented with α- and γ-tocopherol since middle age (15 months). Experiment Overall Design: Gene expressi...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-8146 | biostudies-arrayexpress
TranscriptomicsGlobal profiling of vitamin E deficient mutant vte2 and wild type during low temperature treatment
Tocopherols (vitamin E) are lipid-soluble antioxidants produced by all plants and algae, and many cyanobacteria, yet their functions in these photosynthetic organisms are still not fully understood. We have previously reported that the vitamin E deficient 2 (vte2) mutant of Arabidopsis thaliana is s...
ORGANISM(S): Arabidopsis thaliana 
2014-01-14 | E-GEOD-53990 | biostudies-arrayexpress
Genomicsγ-Tocopherol attenuates COPD-associated macrophage inflammation through the PSEN1–SYT7–PI3K/Akt axis
γ-Tocopherol attenuates COPD-associated macrophage inflammation through the PSEN1–SYT7–PI3K/Akt axis
PRJNA1482019 | ENA
TranscriptomicsExpression data from tocopherol deficient seedlings of Arabidopsis
Tocopherols (Vitamin E) are lipophilic antioxidants that are synthesized by all plants and are particularly abundant in seeds. Two tocopherol deficient mutant loci were used to examine how tocopherol deficiency impacts global gene expression during the critical peroid of germination and early seedli...
ORGANISM(S): Arabidopsis thaliana 
2006-12-29 | GSE4847 | GEO
Transcriptomicsγ-Tocopherol attenuates COPD-associated macrophage inflammation through the PSEN1–SYT7–PI3K/Akt axis
Rationale: Chronic obstructive pulmonary disease (COPD) features persistent airway inflammation, oxidative/nitrative stress, and macrophage activation. γ-tocopherol has antioxidant and anti-inflammatory activity, but its disease relevance and molecular targets are unclear. Objectives: To test whethe...
ORGANISM(S): Mus musculus 
2026-06-26 | GSE336580 | GEO
GenomicsChemifortification of leaves through enhanced metabolic flux to tocopherol biosynthesis and plastoglobule proliferation.
Chemifortification of leaves through enhanced metabolic flux to tocopherol biosynthesis and plastoglobule proliferation.
PRJNA1297610 | ENA
TranscriptomicsChemifortification of leaves through enhanced metabolic flux to tocopherol biosynthesis and plastoglobule proliferation.
Plant biofortification with phytonutrients typically relies on metabolic engineering strategies known as “push” (enhancing biosynthetic flux), “block” (inhibiting competing pathways), and “pull” (promoting metabolite storage). Here, we describe a novel chemifortification approach independent of gene...
ORGANISM(S): Arabidopsis thaliana 
2026-02-19 | GSE303753 | GEO
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