Transcription profiling of mouse brain to identify age-related transcriptional changes and the effect of dietary supplementation of vitamin E

ABSTRACT: We established the transcriptional profile of brain aging and examine the global effects of vitamin E supplementation on age-related alterations in expression in the aged mouse brain. Experiment Overall Design: Gene expression profiles were obtained from the neocortex tissues of 5-month-old controls, 30-month-old controls and 30-month old B6C3F1 mice with middle age-onset supplementation of alpha-tocopherol or a mixture of alpha and gamma-tocopherol (500mg/kg of each tocopherol).

ORGANISM(S): Mus musculus

SUBMITTER: Sang-Kyu Park 

PROVIDER: E-GEOD-8150 | biostudies-arrayexpress |

REPOSITORIES: biostudies-arrayexpress