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GenomicsHuR promotes triglyceride synthesis and intestinal fat absorption
HuR promotes triglyceride synthesis and intestinal fat absorption
PRJNA1093368 | ENA
GenomicsHuR promotes triglyceride synthesis and intestinal fat absorption
HuR promotes triglyceride synthesis and intestinal fat absorption
PRJNA1061476 | ENA
GenomicsInhibition of granuloma triglyceride synthesis imparts control of Mycobacterium tuberculosis through curtailed inflammatory responses
Inhibition of granuloma triglyceride synthesis imparts control of Mycobacterium tuberculosis through curtailed inflammatory responses
PRJNA743689 | ENA
ProteomicsTriglyceride induces ‌endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
Triglyceride synthesis promotes the activation of C-type lectin receptors signaling pathway upon fungal infection‌. Triglyceride synthesis induces endoplasmic reticulum lipid bilayer stress and activates the PERK kinase after fungal stimulation. PERK mediates autophagic degradation of SHP-1 to ampli...
ORGANISM(S): Mus Musculus 
2026-01-12 | PXD072975 |
TranscriptomicsTranscription profiling of mouse liver from JNK knocked down animals
Liver-specific Knockdown of JNK1 Up-regulates Proliferator-activated Receptor Coactivator 1 and Increases Plasma Triglyceride despite Reduced Glucose and Insulin Levels in Diet-induced Obese Mice. The c-Jun N-terminal kinases (JNKs) have been implicated in the development of insulin resistance, dia...
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-7648 | biostudies-arrayexpress
TranscriptomicsFenofibrate increases VLDL-triglyceride production despite reducing plasma triglyceride levels in APOE*3-Leiden.CETP mice
The PPAR? activator fenofibrate efficiently decreases plasma triglycerides (TG), which is generally attributed to enhanced VLDL-TG clearance and decreased VLDL-TG production. However, since data on the effect of fenofibrate on VLDL production are controversial, we aimed to investigate in (more) deta...
ORGANISM(S): Mus musculus 
2010-05-27 | E-GEOD-21211 | biostudies-arrayexpress
ProteomicsHepatic AKAP1 Deficiency Exacerbates Diet-Induced MASLD by Enhancing GPAT1-mediated Lysophosphatidic Acid Synthesis
Metabolic dysfunction-associated steatotic liver disease (MASLD), closely associated with obesity, can progress to metabolic dysfunction-associated steatohepatitis when the liver undergoes overt inflammatory damage. A-kinase anchoring protein 1 (AKAP1) has been shown to control lipid accumulation in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD062388 | Pride
Akap1  masld  lysophosphatidic acid  gpat1  triglyceride synthesis. 
TranscriptomicsTranscription profiling of livers from SCD1 knockout and wild type mice to elucidate the molecular basis of protection against adiposity in mice lacking of stearoyl-CoA desaturase-1 function
Stearoyl-CoA desaturase (SCD) is a central lipogenic enzyme catalyzing the synthesis of monounsaturated fatty acids, mainly oleate (C18:1) and palmitoleate (C16:1), which are components of membrane phospholipids, triglycerides, wax esters, and cholesterol esters. Several SCD isoforms (SCD1-3) exist ...
ORGANISM(S): Mus musculus 
2007-08-31 | E-GEOD-2926 | biostudies-arrayexpress
GenomicsGlucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant
Glucokinase activity suppresses hepatic cholesterol synthesis and triglyceride accumulation: A new model for the effects of the GKRP P466L common human variant
PRJNA1477031 | ENA
TranscriptomicsDirect regulation of myocardial triglyceride metabolism by the cardiomyocyte circadian clock
Maintenance of circadian alignment between an organism and its environment is essential to ensure metabolic homeostasis. Synchrony is achieved by cell autonomous circadian clocks. Despite a growing appreciation of the integral relation between clocks and metabolism, little is known regarding the dir...
ORGANISM(S): Mus musculus 
2010-03-24 | GSE21028 | GEO
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