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TranscriptomicsRNA sequencing–based determination of the RNA interactome of wild-type AKAP1 and its deletion mutants deficient for the KH or Tudor domain.
AKAP1 is highly expressed in glioblastoma and is required for tumor growth. We therefore analyzed the AKAP1 RNA interactome in glioblastoma cells. Native RNA immunoprecipitation followed by high-throughput sequencing (RIP-Seq) was performed in U87MG cells transiently expressing V5-tagged mouse wild-...
ORGANISM(S): Homo sapiens 
2026-09-01 | E-MTAB-16473 | biostudies-arrayexpress
ProteomicsHepatic AKAP1 Deficiency Exacerbates Diet-Induced MASLD by Enhancing GPAT1-mediated Lysophosphatidic Acid Synthesis
Metabolic dysfunction-associated steatotic liver disease (MASLD), closely associated with obesity, can progress to metabolic dysfunction-associated steatohepatitis when the liver undergoes overt inflammatory damage. A-kinase anchoring protein 1 (AKAP1) has been shown to control lipid accumulation in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-26 | PXD062388 | Pride
Akap1  masld  lysophosphatidic acid  gpat1  triglyceride synthesis. 
GenomicsRNA-sequencing analysis reveals mitochondrial dysfunction in Akap1 Knockout mice exposed to hyperoxia
RNA-sequencing analysis reveals mitochondrial dysfunction in Akap1 Knockout mice exposed to hyperoxia
PRJNA725144 | ENA
TranscriptomicsRNA-sequencing analysis reveals mitochondrial dysfunction in Akap1 Knockout mice exposed to hyperoxia
Akap1 KO and Wt mice were exposed to normoxia or hyperoxia for 48h. Total RNA was extracted from lungs of Wt Normoxia (n=3), Wt hyperoxia (n=3), Akap1 KO (n=3) and Akap1 hyperoxia (n=3) mice. RNA-sequencing was carried out followed by differential expression of genes in the following groups. Wt Norm...
ORGANISM(S): Mus musculus 
2022-10-26 | GSE173295 | GEO
GenomicsRNA sequencing–based determination of the RNA interactome of wild-type AKAP1 and its deletion mutants deficient for the KH or Tudor domain.
RNA sequencing–based determination of the RNA interactome of wild-type AKAP1 and its deletion mutants deficient for the KH or Tudor domain.
PRJEB105901 | ENA
UnknownHepatic AKAP1 deficiency exacerbates diet-induced MASLD by enhancing GPAT1-mediated lysophosphatidic acid synthesis.
Not available
S-EPMC12062205 | biostudies-literature
UnknownLoss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure.
Not available
S-EPMC5985454 | biostudies-literature
UnknownAKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission.
Not available
S-EPMC6146498 | biostudies-literature
UnknownAKAP1 contributes to impaired mtDNA replication and mitochondrial dysfunction in podocytes of diabetic kidney disease.
Not available
S-EPMC9274505 | biostudies-literature
UnknownAKAP1 regulates mitochondrial and synaptic homeostasis to enable neuroprotection and repair in retinal ganglion cell degeneration.
Not available
S-EPMC12676536 | biostudies-literature
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