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TranscriptomicsLow Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Molecular Changes That Ooccur to Repair Radiation Damage and Gene Transcripts That May be Involved in Establishing Disease in Mice Post Irradiation
The protozoan parasite Trypanosoma evansi is responsible for causing Surra in a variety of mammalian hosts over a wide geographical area. In order to identify which genes and processes are required to establish disease in mice, parasites were irradiated over a range using a Cobalt60 gamma source. A...
ORGANISM(S): Trypanosoma evansi 
2022-05-10 | E-MTAB-11705 | biostudies-arrayexpress
ProteomicsShotgun proteomics of detergent-solubilized membrane proteins from Trypanosoma evansi
Trypanosoma evansi, the etiological agent of Surra, is the most widespread pathogenic salivarian trypanosomes and affects most livestock and wild animals in endemic regions. Knowledge of the molecular and cell biology of the parasite is limited. The study of proteins through a proteomic-based approa...
ORGANISM(S): Trypanosoma evansi 
2024-07-03 | PXD040594 | Pride
Proteomic Triton-x114 Surface proteins 
ProteomicsTrypanosoma evansi secretome carries potential biomarkers for surra diagnosis
Trypanosoma evansi is a parasite of African origin that has evolutionary proximity to Trypanosoma brucei. This parasite, which causes the surra, has the broadest range of hosts, including wild and domestic mammals, and its geographic distribution is the widest among all trypanosomes. This disease ca...
ORGANISM(S): Trypanosoma evansi 
2023-03-04 | PXD031861 | Pride
Proteomic  bioinformatic  immunoinformatic  epitope 
GenomicsTrypanosoma evansi
Trypanosoma evansi overview
PRJNA1142666 | ENA
TranscriptomicsRNA-seq of C57BL/6 mice splenocytes at chronic stage of Trypanosoma evansi infection
We investigate changes in the single-cell transcriptomic profile of mouse (C57BL/6) splenocytes at late stage of Trypanosoma evansi Merzouga 93 (ITMAS 150399C) infection. Infection was initiated by Intraperitoneal injection with parasites diluted in PBS. On day 42 post-injection, mice spleens were d...
ORGANISM(S): Mus musculus 
2022-10-26 | E-MTAB-12109 | biostudies-arrayexpress
TranscriptomicsLow Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Gene Transcripts Involved in Establishing Disease in Mice Post Irradiation
Transcriptome analysis of irradiated T evansi parasites The protozoan parasite Trypanosoma evansi is responsible for causing Surra in a variety of mammalian hosts over a wide geographical area. In order to identify which genes and processes are required to establish disease in mice, parasites were i...
ORGANISM(S): Trypanosoma evansi 
2023-05-06 | GSE202334 | GEO
GenomicsTrypanosoma evansi isolate:TEDC953
Trypanosoma evansi Isolate: TEDC953 Thai Strain Genome Sequencing
PRJNA1142466 | ENA
TranscriptomicsRNA-seq of C57BL/6 mice splenocytes during Trypanosoma Evansi infection
We investigate changes in the single-cell transcriptomic profile of mouse (C57BL/6) splenocytes during Trypanosoma Evansi Merzoua-93 (ITMAS 150399C) infection. Infection was initiated by Intraperitoneal injection with parasites diluted in PBS. On day 0/14/42 post-injection, mice spleens were disasso...
ORGANISM(S): Mus musculus 
2021-10-26 | E-MTAB-10174 | biostudies-arrayexpress
ProteomicsLandscapes of post-translational modifications in Trypanosoma parasites
Proteins of all living cells undergo a myriad of posttranslational modifications (PTMs) that are critical to multifarious life processes. In this study, we describe the first comprehensive multiple PTM-omics atlas in parallel with quantitative proteome analyses of two representative species of trypa...
ORGANISM(S): Trypanosoma brucei brucei 
2020-06-30 | PXD016425 | Pride
Trypanosoma brucei  trypanosoma evansi  post-translational modification  acetylation  crotonyltion  2-hydroxyisobutyrylation  malonylation  succinylation  ubiquitination  trimethylation  phosphorylation  n-glycosylation  o-glcnacylation 
GenomicsLow Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Gene Transcripts Involved in Establishing Disease in Mice Post Irradiation
Low Dose Gamma Irradiation of Trypanosoma evansi Parasites Identifies Gene Transcripts Involved in Establishing Disease in Mice Post Irradiation
PRJNA835481 | ENA
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