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ProteomicsShotgun proteomics of detergent-solubilized membrane proteins from Trypanosoma evansi
Trypanosoma evansi, the etiological agent of Surra, is the most widespread pathogenic salivarian trypanosomes and affects most livestock and wild animals in endemic regions. Knowledge of the molecular and cell biology of the parasite is limited. The study of proteins through a proteomic-based approa...
ORGANISM(S): Trypanosoma evansi 
2024-07-03 | PXD040594 | Pride
Proteomic Triton-x114 Surface proteins 
ProteomicsQuantitative proteomics analysis of paired colorectal cancer and non-tumorigenic tissues reveal proteins and pathways perturbed in colorectal cancer
Proteomics is a dynamic field emerged dramatically the post genomic era which has been extensively employed to study altered protein expression to gain insight into the development process and pathways involved in cancer and uncover potential protein markers. Membrane proteomes of an expanded cohort...
ORGANISM(S): Homo sapiens (Human) 
2016-06-15 | PXD001676 | Pride
Proteomics Mass spectrometery Colorectal cancer Lc-ms/ms 
ProteomicsCell wall enrichment unveils proteomic changes in the cell wall during treatment of Mycobacterium smegmatis with sub-lethal concentrations of Rifampicin
In this study, we successfully developed two gel-free approaches to specifically look at cell wall proteins in Mycobacterium smegmatis. The cell wall was subjected to differential centrifugation, differential detergent solubilisation and phase separation to yield the genuine cell wall proteome. The ...
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2019-04-09 | PXD008075 | Pride
Cell wall proteomics Mycobacteria Mass spectrometry Rifampicin Tb drugs Tb Sub lethal 
ProteomicsAdherent and Spheroid Glioblastoma Proteomics
Dendritic cell (DC)-based immunotherapy against glioblastoma multiforme is a novel treatment hope. Glioblastoma stem-like cells are, however, potentially causing immunoresistance. Glioblastoma cells cultured as gliomaspheres show a stem-like phenotype as opposed to classical adherent culture. They a...
ORGANISM(S): Homo sapiens (Human) 
2019-04-15 | PXD008244 | Pride
Dendritic cell Immunotherapy Antigen source Gliomasphere Quantitative proteomics Glioblastoma multiforme 
ProteomicsProtein 2DE reference map of Rhodnius prolixus's anterior midgut, part 1
Rhodnius prolixus is one of the most important vectors of Chagas’ disease caused by the parasite Trypanosoma cruzi. Vector control is the principal combat method of this disease. It is inside of intestine that T. cruzi completes his life cycle to become infectious. On this work a 2D protein map of R...
ORGANISM(S): Rhodnius prolixus (Triatomid bug) 
2015-12-14 | PXD001488 | Pride
Midgut 2d-map Rhodnius prolixus 
ProteomicsProtein 2DE reference map of Rhodnius prolixus's anterior midgut, part 2
Rhodnius prolixus is one of the most important vectors of Chagas’ disease caused by the parasite Trypanosoma cruzi. Vector control is the principal combat method of this disease. It is inside of intestine that T. cruzi completes his life cycle to become infectious. On this work a 2D protein map of R...
ORGANISM(S): Rhodnius prolixus (Triatomid bug) 
2015-12-14 | PXD001489 | Pride
Midgut 2d-map Rhodnius prolixus 
ProteomicsLRP1 in Vascular Remodeling and Angiotensin Signaling
Vascular smooth muscle cells (vSMC) exert a critical role in sensing and maintaining vascular integrity. These cells abundantly express the low-density lipoprotein receptor-related protein 1 (LRP1), a large endocytic and signaling receptor that recognizes numerous ligands including ApoE-rich lipopro...
ORGANISM(S): Mus musculus (Mouse) 
2023-03-11 | PXD038236 | Pride
Ace/angiotensin receptors/renin angiotensin system Smooth muscle proliferation and differentiation Vascular biology Lrp1 Tgf-β Sma remodeling Ang ii Hemodynamics Remodeling Animal models of human disease Proteomics Smooth muscle cells 
GenomicsCandida albicans
1.5 and 3 hours macrophage exposure
PRJNA95737 | ENA
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