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GenomicsAdoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen-spreading and elimination of antigen-negative tumor variants
Adoptive transfer of membrane-restricted IL-12-TCR T cells promotes antigen-spreading and elimination of antigen-negative tumor variants
PRJNA1162104 | ENA
ProteomicsQuantitative cell type specific immunopeptidome analysis during macrophage and tumor co-evolution reveals therapeutic MHC-I restricted peptides in glioblastoma
Glioblastoma treatment by immunotherapy is limited by the immunosuppresive tumor microenvironment, in part created by GBM associated macrophages. To uncover targetable MHC-I peptides for targeted immunotherapy, we performed cell type specific immunopeptidome analysis on primary macrophages and GBM t...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-03 | PXD057588 | Pride
Tumor associated macrophage Mhc-i restricted peptides Glioblastoma Immunopeptidome 
UnknownPhosphorylated self-peptides alter human leukocyte antigen class I-restricted antigen presentation and generate tumor-specific epitopes.
Not available
S-EPMC2650342 | biostudies-literature
UnknownIdentification of novel HLA-restricted preferentially expressed antigen in melanoma peptides to facilitate off-the-shelf tumor-associated antigen-specific T-cell therapies.
Not available
S-EPMC8316284 | biostudies-literature
UnknownProcessing sites are different in the generation of HLA-A2.1-restricted, T cell reactive tumor antigen epitopes and viral epitopes.
Not available
S-EPMC2888035 | biostudies-literature
UnknownTumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin.
Not available
S-EPMC2391066 | biostudies-literature
UnknownGlobal analysis of HLA-A2 restricted MAGE-A3 tumor antigen epitopes and corresponding TCRs in non-small cell lung cancer.
Not available
S-EPMC10465222 | biostudies-literature
UnknownImmunological evaluation of a novel HLA-A2 restricted phosphopeptide of tumor associated Antigen, TRAP1, on cancer therapy.
Not available
S-EPMC6668235 | biostudies-literature
UnknownProbiotic lactic acid bacteria promote anti-tumor immunity through enhanced major histocompatibility complex class I-restricted antigen presentation machinery in dendritic cells.
Not available
S-EPMC11008462 | biostudies-literature
TranscriptomicsModeling tumor subtypes in vivo using lineage restricted transgenic shRNA
Expression analysis from two genetically engineered mouse models of osteosarcoma determine the expression profile of mouse osteosarcoma Human osteosarcoma (OS) is comprised of three different subtypes: fibroblastic, chondroblastic and osteoblastic. We previously generated a mouse model of fibroblast...
ORGANISM(S): Mus musculus 
2013-03-28 | E-GEOD-38742 | biostudies-arrayexpress
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