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ProteomicsEnrichment of proteins in purified Saccharomyces cerevisiae vacuoles relative to a whole cell extract.
The project sought to test the localization of several proteins that were suspected to be in vacuoles. To this end, the proteomes of whole cells and of a purified vacuolar fraction were quantified to estimate the enrichment factors of established vacuolar markers and compare them to the enrichment o...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-09-19 | PXD060102 | Pride
Yeast Organelle proteome Pho91 Vacuole 
ProteomicsSerine ubiquitination of SNAREs generates bacterial vacuoles and prevents their lysosomal fusion
Here we show that Legionella SidE effectors mediate phosphoribosyl-linked serine ubiquitination (PR-Ub) of the autophagic SNARE proteins STX17 and SNAP29. On the one hand, PR-Ub modification of STX17 enhances its interaction with ATG14L, which drives the recruitment of ER membranes to the bacterial ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-14 | PXD058184 | Pride
Legionella pneumophila Xenophagy Syntaxin17 Ubiquitin Autophagy 
ProteomicsIdentification of proteins from vacuoles of red algae
Vacuoles and lysosomes are single-membrane-bound organelles involved in diverse functions such as intracellular digestion and storage or secretion of metabolites. To understand their origin, evolution and fundamental features, the identification of proteins comprising these compartments in missing l...
ORGANISM(S): Cyanidioschyzon merolae strain 10D 
2009-09-01 | GSE12042 | GEO
UnknownVacuoles in Bryophytes: Properties, Biogenesis, and Evolution.
Not available
S-EPMC9209779 | biostudies-literature
UnknownHuman Sperm Head Vacuoles Are Related to Nuclear-Envelope Invaginations.
Not available
S-EPMC10298367 | biostudies-literature
GenomicsCyanidioschyzon merolae strain 10D
Identification of proteins from vacuoles of red algae
PRJNA113367 | ENA
ProteomicsSNAP47 acetylation-dependent regulatory mechanism governing autophagosome-lysosome fusion by modulating the recruitment of HOPS to autophagic vacuoles
Autophagy, a conserved catabolic process implicated in a diverse array of human diseases, requires efficient fusion between autophagosomes and lysosomes to function effectively. Recently, SNAP47 has been identified as a key component of the default SNARE complex mediating autophagosome-lysosome fusi...
ORGANISM(S): Homo Sapiens 
2024-05-13 | PXD052239 |
UnknownRimmed vacuoles in Becker muscular dystrophy have similar features with inclusion myopathies.
Not available
S-EPMC3522649 | biostudies-literature
UnknownThe entry of unclosed autophagosomes into vacuoles and its physiological relevance.
Not available
S-EPMC9562215 | biostudies-literature
UnknownNotochord vacuoles absorb compressive bone growth during zebrafish spine formation.
Not available
S-EPMC7012607 | biostudies-literature
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