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TranscriptomicsTranscription profiling of rat left ventricular samples from 12-, 16- and 20-month old spontaneously hypertensive rats (SHRs) compared with age-matched Wistar-Kyoto (WKY) rats as controls
Left ventricular gene expression profiles from 12-, 16- and 20-months old spontaneously hypertensive rats (SHRs) were compared with left ventricular profiles seen in age-matched Wistar-Kyoto (WKY) rats [control rats] by screening Affymetrix U34A arrays (there are 4 samples in each timepoint except 3...
ORGANISM(S): Rattus norvegicus 
2007-09-20 | E-GEOD-2116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of liver from wistar and kyoto rats exposed to orotic acid to investigate fatty liver disease
Although fatty liver disease is caused by a number of toxicological insults and the metabolic syndrome, the exact mechanisms by which many of these pathophysiological stimulii induce fatty liver are unknown. The rapid and profound steatosis caused by orotic acid, resulting from an impairment in the ...
ORGANISM(S): Rattus norvegicus 
2009-03-11 | E-BIID-1 | biostudies-arrayexpress
TranscriptomicsTranscription profiling time series of orotic acid induced fatty liver disease in Rattus norvegicus
A time course of orotic acid induced fatty liver disease. Kyoto and Wistar strain rats were exposed to orotic acid for days 1, 3 and 14. Controls are also included.
ORGANISM(S): Rattus norvegicus 
2007-10-11 | E-GEOD-665 | biostudies-arrayexpress
TranscriptomicsExpression data from kidneys of rats with and without glomerulonephritis
We investigated a glomerulonephritis (GN) model in rats induced by nephrotoxic serum (NTS) which contains antibodies against the glomerular basement membrane (GBM). The anti-GBM GN model in rats is widely used since its biochemical and histopathological characteristics are similar to crescentic neph...
ORGANISM(S): Rattus norvegicus 
2015-07-06 | E-GEOD-64265 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hypertensive and normotensive rats treated with the AT1 receptor antagonist candesartan and vehicle
In hypertension, abnormal regulation of microcirculation and endothelial dysfunction enhances vulnerability to hypertensive brain damage. In addition to lowering blood pressure, blockade of Angiotensin II AT1 receptors protects against stroke and stress in different animal models and this treatment ...
ORGANISM(S): Rattus norvegicus 
2007-11-03 | E-GEOD-2739 | biostudies-arrayexpress
TranscriptomicsMicroarray gene profiling in glucocorticoid-induced Avascular Necrosis of the Femoral Head in a Rat Model
Wistar Kyoto Rats were administered glucocorticoid pellets and placebo pellets for 6 months. After 6 months rats were sacrificed and their femoral heads were histologically examined for the detection of avascular necrosis of the femoral head. Total RNA was extracted from femoral heads and submitted ...
ORGANISM(S): Rattus norvegicus 
2011-06-09 | E-MEXP-2751 | biostudies-arrayexpress
MetabolomicsKidney protective effect of fermented celery polysaccharides and Eubacterium rectale in diabetic rats

This study aimed to investigate the protective effects of non-fermented celery polysaccharides (NFCP), fermented celery polysaccharides (FCP), Eubacterium rectale (ER), and their combined intervention (ER+FCP) on Type 2 diabetes (T2D)-related kidney injury in a rat model, using untargeted urinary...

2026-03-02 | MTBLS13958 | MetaboLights
GenomicsRattus norvegicus strain:Wistar-Kyoto
MBD-seq in stressreactive Wistar Kyoto rats exposed to neonatal maternal separation
PRJNA344754 | ENA
MetabolomicsThe Relative Content and Distribution of Absorbed Volatile Organic Compounds in Rats Administered Asari Radix et Rhizoma Are Different between Powder- and Decoction-Treated Groups
Asari Radix et Rhizoma (ARR) is an important traditional Chinese medicine. Volatile organic compounds (VOCs) are the main active constituents of ARR. Research on the metabolite profile of VOCs and the difference of absorbed constituents in vivo after an administration of ARR decoction and powder wil...
2021-02-01 | MTBLS2053 | MetaboLights
TranscriptomicsTranscription profiling of rat adrenal glands from spontaneously hypertensive (SHR) and normotensive Wistar-Kyoto animals
We measured gene expression in the adrenal glands of the Spontaneously Hypertensive Rat (SHR) and Wistar-Kyoto rat (WKY) using Affymetrix RG-U34A GeneChips. All rats were aged-matched at 4-weeks. The rats were obtained from the colonies at the Univeristy of California San Diego, La Jolla, CA.
ORGANISM(S): Rattus norvegicus 
2007-11-01 | E-GEOD-1675 | biostudies-arrayexpress
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