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MetabolomicsUntargeted UPLC-MS/MS metabolomics of zebrafish gut tissue after chronic ciprofloxacin exposure
This project provides untargeted metabolomics data of zebrafish gut tissue from adult wild-type AB strain zebrafish (Danio rerio) under control conditions and chronic ciprofloxacin (CIP) exposure at 5,000 ng/L for 30 days.
2026-09-09 | MTBLS15610 | MetaboLights
MetabolomicsMetabolomic Responses to Circadian Rhythm Disruption in Zebrafish

Circadian rhythms are essential biological oscillators that synchronize physiological processes, cellular homeostasis, and systemic metabolism with the Earth's natural 24-hour light-dark cycle. While circadian rhythm disruption (CRD) is highly prevalent in modern society due to factors such as sh...

2026-06-23 | MTBLS14815 | MetaboLights
TranscriptomicsDanio rerio larvae exposed to SSRIs Fluoxetine and Sertraline
Pharmaceutical chemicals used in human medicine are released into surface waters via municipal effluents and pose a risk for aquatic organisms. Among these substances are selective serotonin reuptake inhibitors (SSRIs) which can affect aquatic organisms at sub ppb concentrations. To better underst...
ORGANISM(S): Danio rerio 
2012-09-06 | E-GEOD-31712 | biostudies-arrayexpress
ProteomicsProteome changes in larval zebrafish (Danio rerio) and fathead minnow (Pimephales promelas) exposed anatoxin-a fumerate.
Characterization of proteome changes to zebrafish and fathead minnow following exposure to the Anatoxin-a surrogate anatoxin-fumerate.
ORGANISM(S): Pimephales Promelas (ncbitaxon:90988) Danio Rerio (ncbitaxon:7955) 
2023-11-29 | MSV000093536 | MassIVE
MetabolomicsA robust method for performing 1H-NMR lipidomics in embryonic zebrafish
The embryonic zebrafish is an ideal system for lipid analyses with relevance to many areas of bioscience research, including biomarkers and therapeutics. Research in this area has been hampered by difficulties in extracting, identifying and quantifying lipids. We employed 1H-NMR at 700MHz to profile...
2024-07-02 | MTBLS2396 | MetaboLights
ProteomicsZnf598-mediated Rps10/eS10 Ubiquitination contributes to the ribosome ubiquitination dynamics during zebrafish development
The ribosome is a translational apparatus that comprises about 80 ribosomal proteins and four rRNAs. Recent studies reported that ubiquitination of the ribosomal proteins plays a pivotal role in translational control and ribosome-associated quality control (RQC). However, little is known about the d...
ORGANISM(S): Danio Rerio 
2023-10-11 | PXD039560 | JPOST Repository
TranscriptomicsRNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of Triiodothyronine (T3) below acute toxicity levels against untreated control groups
The aim of this sequencing experiment was to screen for ecotoxicogenomic fingerprints for endocrine disrupting chemicals affecting the thyroid system in zebrafish (Danio rerio) embryos as aquatic vertebrate model and alternative to animal testing. Triiodothyronine (T3, CAS: 6893-02-3) was tested as ...
ORGANISM(S): Danio rerio 
2020-09-30 | E-MTAB-9056 | biostudies-arrayexpress
TranscriptomicsRNA-Seq of zebrafish embryos (96hpf) treated with different concentrations of 6-Propyl-2-thiouracil (6-PTU) below acute toxicity levels against untreated control groups
Endocrine disruption can trigger far-reaching effects on environmental populations, justifying a refusal of market approval for chemicals with ED properties. Ecotoxicogenomic screening was performed to identify molecular fingerprints for endocrine disrupting chemicals affecting the thyroid system in...
ORGANISM(S): Danio rerio 
2020-09-30 | E-MTAB-9054 | biostudies-arrayexpress
TranscriptomicsMapping of H3K4 and H3K27 trimethylation in zebrafish cells (Gene expression)
The genomic distribution of post-translationally modified histones in the zebrafish (Danio rerio) genome remain largely unraveled. The objective of this study was to (1) design a microarray covering all zebrafish gene promoters and 5' end of coding regions, and (ii) using these arrrays, map the geno...
ORGANISM(S): Danio rerio 
2011-02-08 | E-GEOD-23679 | biostudies-arrayexpress
MetabolomicsMyocardial-intrinsic defects underlie an Rbfox-mediated zebrafish model of hypoplastic left heart syndrome
Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of left sided structures including the ventricle, valves, and aorta1. Although the mechanisms of disease pathogenesis remain elusive due to a paucity of candidate genes and animal models, prevailing paradigm suggests that HL...
2022-07-12 | MTBLS4176 | MetaboLights
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