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MetabolomicsAppropriate taxonomic classification of intestinal microbiome by 16S rRNA gene targeting metagenomic approach
16S metagenomic analysis has provided much information about the intestinal microbiome. However, there are no reports that describe their appropriate taxonomic classification rank. Moreover, studies differ on the taxonomic ranking of the same microorganism. Intestinal microbiome exerts a significant...
2017-02-20 | MTBLS376 | MetaboLights
MetabolomicsFunctional potential of gut microbiota in Rhinolophus ferrumequinum revealed by 16S rRNA sequencing and metabolomics
Insectivorous bats depend on insects while sustaining high-energy flight and specialised immune tolerance. Gut microbiota may contribute to host energy utilisation and immune regulation, but their functions remain unclear. We investigated the greater horseshoe bat (Rhinolophus ferrumequinum) using 1...
2026-09-13 | MTBLS14955 | MetaboLights
MetabolomicsMetabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa
Not available
ORGANISM(S): Homo sapiens 
ST001087 | MetabolomicsWorkbench
MetabolomicsDysbiosis of Gut Microbiota and Metabolomic Alterations in Myasthenia Gravis: Insights from 16S rRNA Sequencing and Untargeted Metabolomics

Background: Myasthenia gravis (MG) is an autoimmune disorder of neuromuscular transmission. Gut dysbiosis has been implicated in autoimmune pathogenesis, yet integrated microbial and metabolomic profiling in MG remains scarce.

Objectives:  To characterize gut microbiota and t...

2026-04-13 | MTBLS14266 | MetaboLights
MetabolomicsPolicosanol Alleviates Chronic Stress-Induced Growth Impairment via Gut Microbiota-Metabolite Interactions: Insights from 16S rRNA Sequencing and LC-MS Metabolomics

Background/Objectives: Policosanol, a bioactive compound derived from rice bran wax, has demonstrated potential for alleviatingshown potential in combating stress, yet its underlying mechanisms remain elusive. This study aimed to elucidate its role in mitigating chronic stress-induced growth impa...

2025-10-21 | MTBLS13189 | MetaboLights
MetabolomicsPreliminary exploration of the ability of HUC-MSCs to restore the lung microbiota and related metabolite disorders in IPF treatment: Combining 16S sequencing and metabolite analysis

Abstract

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive pulmonary disease, and effective therapies to reverse the natural course of IPF are lacking. A growing number of studies have shown that the use of human umbilical cord-derived mesenchymal stem cells (HUC-...

2025-09-01 | MTBLS12922 | MetaboLights
MetabolomicsA Combined LC-MS Metabolomics- and 16S rRNA Sequencing Platform to Assess Interactions between Herbal Medicinal Products and Human Gut Bacteria in Vitro: a Pilot Study on Willow Bark Extract
Herbal preparations are complex mixtures of natural products, many of which are able to reach the distal gut. There, they influence the microbial communities, and can be metabolized into bioactive metabolites. The aim of this study was to establish an interdisciplinary platform to unravel interactio...
2017-12-14 | MTBLS479 | MetaboLights
MetabolomicsResearch on the microbiota and metabolic characteristics of type 2 chronic rhinosinusitis based on the analysis of 16S amplicon sequencing combined with metabolomics

Objective:

To investigate the diversity of nasal microbiota and metabolic characteristics of patients with Type 

2 chronic rhinosinusitis, as well as the interactions and potential regulatory relationships between 

the nasal microbiota and their metabolites by conducti...

2025-10-21 | MTBLS13192 | MetaboLights
MetabolomicsRevealing the Social Biomarkers of Residual Feed Intake by Using 16s rRNA and LC-MS/MS in Duroc Pig
Not available
ORGANISM(S): Sus scrofa 
ST002210 | MetabolomicsWorkbench
ProteomicsPytheas E. coli 16S rRNA sample analysis
Mass spectrometry remains an important method for analysis of modified nucleosides ubiquitously present in cellular RNAs, in particular for ribosomal and transfer RNAs that play crucial roles in mRNA translation and decoding. Furthermore, modifications have effect on the lifetimes of nucleic acids i...
ORGANISM(S): Escherichia coli 
2022-05-04 | PXD030538 | Pride
16s Rna Ribosome Isotope labeling Pytheas 
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