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Transcriptomics2-Deoxyglucose induced transcription in control and MondoA knockdown cells
To determine the contibution of the transcription factor MondoA to 2-deoxyglucose-induced transcription expression analysis was carried out in control and MondoA knockdown cells HA1ER cells are human embryonic kidney cells transformed with hTERT, SV40 Early region and activated H-Ras Keywords: cell ...
ORGANISM(S): Homo sapiens 
2008-04-24 | E-GEOD-11242 | biostudies-arrayexpress
ProteomicsProteomic response of yeast cells to 2-deoxyglucose exposure (0.2%, 2.5h)
Cancer cells display an altered metabolism with increased glycolysis and glucose uptake. Anti-cancer strategies targeting glycolysis through metabolic inhibitors have been considered. The glucose analog 2-deoxyglucose (2DG) is imported into cells and after phosphorylation becomes 2DG-6-phosphate, a ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-09-09 | PXD014373 | Pride
2-deoxyglucose Saccharomyces cerevisiae 
ProteomicsA genetic screen reveals a key role for Reg1 in 2-deoxyglucose sensing and yeast AMPK inhibition
The yeast Saccharomyces cerevisiae thrives in sugar-rich environments by rapidly consuming glucose and favoring alcoholic fermentation. This strategy is tightly regulated by the glucose repression pathway, which prevents the expression of genes required for the utilization of alternative carbon sour...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-10-03 | PXD068555 | Pride
Glucose signaling Yeast 2-deoxyglucose Ampk Pp1 
GenomicsEffect of 2-deoxyglucose on the interferon gamma-mediated response to intracellular bacterial infection in mouse bone marrow-derived macrophages
Effect of 2-deoxyglucose on the interferon gamma-mediated response to intracellular bacterial infection in mouse bone marrow-derived macrophages
PRJNA558699 | ENA
GenomicsUntargeted transcriptomic profiling of activated primary human CD4+ T cells treated with metformin and 2-deoxyglucose
Untargeted transcriptomic profiling of activated primary human CD4+ T cells treated with metformin and 2-deoxyglucose
PRJNA605014 | ENA
TranscriptomicsEffect of 2-deoxyglucose on the interferon gamma-mediated response to intracellular bacterial infection in mouse bone marrow-derived macrophages
We report transcriptional responses of mouse macrophages to Pam3CSK4 stimulation or L. pneumophila infection that are additionally stimulated with interferon gamma ± 2-deoxyglucose. We identify a strong transcriptional signature of the unfolded protein stress response in macrophages exposed to 2-deo...
ORGANISM(S): Mus musculus 
2019-08-09 | GSE135385 | GEO
TranscriptomicsRNAseq of memory cocktail versus IL-2 grown OT-I CD8 T cells
Cytotoxic T cells are typically expanded ex vivo for adoptive immunotherapy by culture with IL-2. This culture period leads to a differentiated phenotype and acquisition of effector function, as well as a loss of in vivo proliferative capability and anti-tumor efficacy. Here, we report antigen-spec...
ORGANISM(S): Mus musculus 
2014-08-12 | E-GEOD-54877 | biostudies-arrayexpress
Transcriptomics2-Deoxyglucose induced transcription in control and MondoA knockdown cells
To determine the contibution of the transcription factor MondoA to 2-deoxyglucose-induced transcription expression analysis was carried out in control and MondoA knockdown cells HA1ER cells are human embryonic kidney cells transformed with hTERT, SV40 Early region and activated H-Ras Keywords: cell ...
ORGANISM(S): Homo sapiens 
2008-04-24 | GSE11242 | GEO
Genomics
2-deoxyglucose resistance in Saccharomyces cerevisiae
PRJNA609347 | ENA
TranscriptomicsUntargeted transcriptomic profiling of activated primary human CD4+ T cells treated with metformin and 2-deoxyglucose
Purpose: To investigate the effects of metabolic inhibitors metformin and 2-deoxyglucose on the global transcriptome of primary human CD4+ T cells. Methods: mRNA profiles of primary human CD4+ T cells were generated by RNA-Seq for 3 donors in triplicate using Illumina TruSeq library prep. Data was p...
ORGANISM(S): Homo sapiens 
2020-06-15 | GSE144353 | GEO
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