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MetabolomicsA gut microbiota–20-HETE lipid signaling axis drives neuroinflammation and anxiety after TBI

A gut microbiota–20-HETE lipid signaling axis drives neuroinflammation and anxiety after TBI


Probiotic L. reuteri attenuates neuroinflammation and anxiety symptoms through gut-brain axis via a novel metabolite 20-HETE in blast-induced traumatic brain injury

2026-07-17 | MTBLS15072 | MetaboLights
TranscriptomicsEffect of 20-Hete and dietary restriction on murine kidneys
Transcriptomic dataset of 15 murine kidneys of 14-week-old male C57Bl6 mice. Mice were divided into 3 treatment groups four weeks prior to nephrectomy and 5 mice had ad libitum (AL) access to food and water, while another 10 mice received 30% food restriction (CR). Calorically restricted mice either...
ORGANISM(S): Mus musculus 
2022-05-10 | E-MTAB-11428 | biostudies-arrayexpress
ProteomicsAnalysis of 20-HETE supplementation in calorically restricted C57Bl6 mice
Proteomic dataset of 15 murine kidneys of 14-week-old male C57Bl6 mice. Mice were divided into 3 treatment groups four weeks prior to nephrectomy and 5 mice had ad libitum access to food and water, while another 10 mice received 30% food restriction. Calorically restricted mice either received intra...
ORGANISM(S): Mus musculus (Mouse) 
2022-06-17 | PXD031604 | Pride
C57bl6 20-hete  caloric restriction Preconditioning 
GenomicsEffect of 20-Hete and dietary restriction on murine kidneys
Effect of 20-Hete and dietary restriction on murine kidneys
PRJEB50798 | ENA
Unknown20-HETE contributes to ischemia-induced angiogenesis.
Not available
S-EPMC4939128 | biostudies-literature
Unknown20-Hydroxyeicosatetraenoic acid (20-HETE): Bioactions, receptors, vascular function, cardiometabolic disease and beyond.
Not available
S-EPMC10683332 | biostudies-literature
UnknownThe role of 20-HETE in androgen-mediated hypertension.
Not available
S-EPMC3248593 | biostudies-literature
UnknownAndrogen-sensitive hypertension associates with upregulated vascular CYP4A12-20-HETE synthase.
Not available
S-EPMC3736709 | biostudies-literature
Unknown20-HETE in the regulation of vascular and cardiac function.
Not available
S-EPMC6278600 | biostudies-literature
Unknown20-HETE-producing enzymes are up-regulated in human cancers.
Not available
S-EPMC3601443 | biostudies-literature
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