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Transcriptomicsrenal damage in 24w2k1c v cont24w
The experiment was designed to study the effects of blood pressure on gene expressions in the kidney cortex. Non-clipped kidney cortex was harvested from eight 2k1c rats and eight sham rats after 4 and 24 weeks of clipping. The 2k1c is the experimental group which underwent a two kidney, one clip (2...
ORGANISM(S): Rattus norvegicus 
2014-11-11 | E-MTAB-1449 | biostudies-arrayexpress
UnknownModerate Physical Exercise Activates ATR2 Receptors, Improving Inflammation and Oxidative Stress in the Duodenum of 2K1C Hypertensive Rats.
Not available
S-EPMC8588860 | biostudies-literature
UnknownAlteration of the Gut Microbiota and Its Effect on AMPK/NADPH Oxidase Signaling Pathway in 2K1C Rats.
Not available
S-EPMC6556358 | biostudies-literature
TranscriptomicsGene expression in the mesenteric arteries of SHR and SHRSP compared with WKYs treated with 2K1C or 1K1C, or without operation for 3 weeks at 6 weeks of age
We examined gene expression profiles in the rat mesenteric arteries using genome-wide microarray technology, and determined gene expression profiles in 3 rat strains and treated ones: spontaneously hypertensive rats (SHR), stroke-prone SHR (SHRSP), and normotensive WKYs treated with 2K1C or 1K1C, or...
ORGANISM(S): Rattus norvegicus 
2019-03-19 | GSE74288 | GEO
UnknownExercise Normalized the Hippocampal Renin-Angiotensin System and Restored Spatial Memory Function, Neurogenesis, and Blood-Brain Barrier Permeability in the 2K1C-Hypertensive Mouse.
Not available
S-EPMC9146761 | biostudies-literature
UnknownCrataeva nurvala Bark (Capparidaceae) Extract Modulates Oxidative Stress-Related Gene Expression, Restores Antioxidant Enzymes, and Prevents Oxidative Stress in the Kidney and Heart of 2K1C Rats.
Not available
S-EPMC10432060 | biostudies-literature
UnknownEffects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension.
Not available
S-EPMC7941277 | biostudies-literature
ProteomicsDistinct protein signature of hypertension-induced damage in the renal proteome of the two-kidney, one-clip ratmodel
Background: Hypertensive nephrosclerosis is one of the most frequent causes of chronic kidney failure. Proteome analysis potentially improves the pathophysiological understanding and diagnostic precision of this disorder. In the present exploratory study, we investigated experimental nephrosclerosis...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-02-28 | PXD012889 | Pride
Hypertension 2k1c Juxtamedullary cortex Kidney 
UnknownProlonged Administration of Rudgea viburnoides (Cham.) Benth. Prevents Impairment of Redox Status, Renal Dysfunction, and Cardiovascular Damage in 2K1C-Hypertensive Rats by Inhibiting ACE Activity and NO-GMPC Pathway Activation.
Not available
S-EPMC8537958 | biostudies-literature
GenomicsRattus norvegicus
Gene expression in the mesenteric arteries of SHR and SHRSP compared with WKYs treated with 2K1C or 1K1C, or without operation for 3 weeks at 6 weeks of age
PRJNA299673 | ENA
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