Sort   by:  
 Page size 
Using affinity purification for the detection of RNA-binding proteins in tapasin 3'UTR
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD045056 | Pride
In eukaryotes, the 3' ends of RNA polymerase II-generated transcripts are made in the majority of cases by site-specific endonucleolytic cleavage, followed by the addition of a poly(A) tail. By alternative polyadenylation, a gene can give rise to multiple mRNA isoforms that differ in the length of t...
ORGANISM(S): Homo sapiens 
Alternative polyadenylation is an important cellular mechanism that enables generation of mRNA isoforms that differ in their 3' untranslated regions (3' UTRs) and consequently in their susceptibility to miRNA and RNA binding protein mediated regulation. A dramatic change in polyadenylation site usa...
ORGANISM(S): Homo sapiens 
Intermolecular 3′UTR-3′UTR interactions drive Wnt gene activation through heteromeric protein assembly
3'UTR sequencing of C.elegans strains
The 3' untranslated regions (3' UTRs) of mRNAs contain cis-acting elements for posttranscriptional regulation of gene expression. Here, we report that mouse genes tend to express mRNAs with longer 3' UTRs as embryonic development progresses. This global regulation is controlled by alternative polyad...
ORGANISM(S): Mus musculus 
Genome-wide maps in MCF-7 cells with six2 or CYP4Z1 3'UTR or CYP4Z2P 3'UTR overexpression or not
Piwi-interacting RNAs (piRNAs) are ~24-30 nucleotide regulatory RNAs that are abundantly expressed in gonads. The most well-understood piRNAs mediate post-transcriptional defense against transposable elements (TEs), and derive from sense or antisense strands as a consequence of "ping-pong"...
ORGANISM(S): Drosophila melanogaster 
Single cell 3'UTR sequencing of neural stem cells
RNA-mediated control of virulence gene expression is widespread among pathogenic bacteria. However, in some major human pathogens such as Streptococcus pneumoniae, its role remains poorly understood. In this study we identify a regulatory function for the 3’-untranslated region (3’UTR) of the mRNA e...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2026-05-27 | PXD040356 | Pride
Sort   by:  
 Page size