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Comprehensive characterization of platelets involves various different functional assays and analysis techniques, each requiring individual aliquots of sample. Consequently, the available sample material is often limited rendering more effective sample use highly important. Our re-cently introduced ...
ORGANISM(S): Homo sapiens (Human) 
2025-02-14 | PXD028316 | Pride
Major advances have been made to develop an automated universal 384-well plate sample preparation platform with high reproducibility and adaptability for extraction of proteins from cells within a culture plate. An in-solution digest strategy is employed to generate peptides from the extracted prote...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD019733 | Pride
This study investigates transcriptional responses of retinal pigment epithelium (RPE) cells from human induced pluripotent stem cell (iPSC) lines MBE-03587 and MBE-03590 following treatment with small molecule compounds with reported mitochondrial or signalling effects. RPE cells were treated with ...
ORGANISM(S): Homo sapiens 
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062313 | Pride
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062275 | Pride
Large scale plasma proteomics studies offer tremendous potential for biomarker discovery but face significant challenges in balancing analytical depth, throughput and cost effectiveness. We present an optimized perchloric acid based workflow with neutralization – PCA N – that addresses these limitat...
ORGANISM(S): Homo sapiens (Human) 
2025-09-30 | PXD062274 | Pride
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