3t3 cell line - OmicsDI

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CHEBI ID

CHEBI:16192 (2)
CHEBI:17256 (2)
CHEBI:16856 (2)
CHEBI:4170 (2)
CHEBI:16235 (2)
CHEBI:61204 (2)
CHEBI:15843 (2)
CHEBI:53486 (2)
CHEBI:16027 (2)
CHEBI:17712 (2)
CHEBI:18005 (1)
CHEBI:36264 (1)
CHEBI:36217 (1)
CHEBI:18391 (1)
CHEBI:33885 (1)
CHEBI:170068 (1)
CHEBI:170066 (1)
CHEBI:138904 (1)
CHEBI:136198 (1)
CHEBI:132677 (1)
CHEBI:136247 (1)
CHEBI:145847 (1)
CHEBI: 136169 (1)
CHEBI:138521 (1)
CHEBI:89602 (1)
CHEBI:88906 (1)
CHEBI:89539 (1)
CHEBI:89536 (1)
CHEBI:171655 (1)
CHEBI:171654 (1)

Metabolite Name

Keto-D-fructose 6-phosphate (1)
3-sulfopyruvic acid (1)
Palmitoyl-CoA (1)
Keto-phenylpyruvate (1)
Menadione (1)
7H-purine (1)
Isocaproic acid (1)
N(2)-acetyl-L-lysine (1)
Beta-cellobiose (1)
NMN zwitterion (1)
Alpha-D-Glcp-(1->4)-alpha-D-Glcp-(1->4)-D-Glcp (1)
Thiamine(1+) diphosphate (1)
UDP-alpha-D-glucuronic acid (1)
2,3-bisphospho-D-glyceric acid (1)
Molybdate (1)
Alpha-D-galacturonic acid (1)
3-hydroxy-1-benzopyran-2-one (1)
3'-dephospho-CoA (1)
Geranyl diphosphate (1)
Isobutyryl-CoA (1)
N(omega),N(omega)-dimethyl-L-arginine (1)
4-hydroxy-3-methylbenzoic acid (1)
Taurodeoxycholic acid (1)
Ursodeoxycholic acid (1)
L-homocysteine (1)
(3S)-3-hydroxy-3-methylglutaryl-CoA (1)
Lactulose (1)
Butyryl-CoA (1)
ADP alpha-D-glucoside (1)
N-acetyl-L-glutamine (1)

First Public Date

2014 (15)
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2019 (3)
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Modification

N6 (1)
N6-dimethyl-L-lysine (1)

Study type

Transcription profiling by array (76)
RNA-seq of coding RNA (13)
ChIP-seq (12)
Other (7)
Transcription profiling by tiling array (3)
RNA-seq of coding RNA from single cells (3)
RNA-seq of non coding RNA (3)
Unknown experiment type (2)
RNAi profiling by array (2)
Comparative genomic hybridization by array (2)
Methylation profiling by array (2)
ChIP-chip by tiling array (1)
Cell line - One-color microarray (1)
Animal - High-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2012 (30)
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2013 (14)
2009 (12)
2008 (8)
2007 (7)
2006 (6)
2005 (4)
2004 (4)
2002 (3)
2003 (2)
1998 (2)
1997 (2)
2000 (1)
1999 (1)

Lab affiliation

1Gavin Herbert Eye Institute –Brunson Center for Translational Vision Research, Department of Ophthalmology and Visual Sciences, University of California Irvine, Irvine, CA 92697, USA 2Department of Physiology and Biophysics, University of California Irvine, Irvine, CA 92697, USA 3Department of Chemistry, University of California Irvine, Irvine, CA 92697, USA 4Department of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, USA (1)
Amsterdam UMC location University of Amsterdam, Department of Medical Biochemistry, Amsterdam, the Netherlands. (1)
Associate Professor Dept of Cell Physiology & Metabolism Centre Médical Universitaire 1, Rue Michel-Servet 1211 Geneva, Switzerland (1)
CIB-CSIC (Spanish Research Council) (1)
Cell Biology Harvard Medical School USA (1)
Central European Institute of Technology, Masaryk University, Brno, Czech Republic (1)
Cleveland Clinic Lerner Research Institute (1)
Institute of Bioengineering, EPFL (1)
Institute of Bioengineering, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne 1015, Switzerland (1)
Max Planck Institute of Biochemistry, Martinsried, Germany (1)
Michael Popp Institute, University of Innsbruck, Austria (1)
Novo Nordisk Foundation Center for Protein Research Faculty of Health & Medical Sciences University of Copenhagen Blegdamsvej 3B DK-2200 Copenhagen N Denmark (1)
Reader | Centre for Genomics and Computational Biology Barts Cancer Institute Queen Mary, University of London John Vane Science Centre, Charterhouse Square, London EC1M 6BQ Tel: +44 (0)20 7882 8266 (1)
Stem Cell Medicine, Functional Phosphoproteomics Lab, Murdoch Children's Research Institute, Australia (1)
Target Discovery Institute University of Oxford (1)
The Charles Perkins Centre, University of Sydney, Australia (1)
Ulm University, Institute of Experimental Physics, Ulm, Baden-Württemberg, 89081, Germany (1)

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Targeting secreted MDK-mediated tryptophan/kynurenine metabolism enhances DLL3 CAR T therapy for SCLC

Small cell lung cancer (SCLC) exhibits profound immunometabolic suppression that impairs antigen presentation and constrains immunotherapy efficacy. Through integrated multi-omics analyses of primary human SCLC tumors, we identified midkine (MDK) as a dominant tumor-secreted driver of immune evas...

2026-03-23 | MTBLS14116 | MetaboLights

Mechanistic analysis of the model obesogen Tributyltin in the 3T3-L1 cell line

Obesogenic compounds are chemicals that might have an influence on obesity development through in utero or chronic lifetime exposure. Tributyltin (TBT) is one of the most studied obesogenic compounds, inducing adipogenesis in vitro and increasing body fat after in utero exposure of mice. This study ...

ORGANISM(S): Mus musculus

2013-02-25 | E-GEOD-41340 | biostudies-arrayexpress

Differences in gene expression patterns in mouse embryonic fibroblast Flp-In-3T3 cell lines stably expressing Pax6 or Pax6(5a).

Novel target genes for the two transcription factor isoforms Pax6 and Pax6(5a) were identified by generating mouse embryonic fibroblast cell lines stably expressing either Pax6 or Pax6(5a), and comparing their gene expression pattern with the original mouse embryonic fibroblast cell line. Flp-In-3T3...

ORGANISM(S): Mus musculus

2012-03-22 | E-GEOD-31402 | biostudies-arrayexpress

In vitro carcinogenicity testing with Balb/c 3T3 Cells treated with various chemical carcinogens

Background: Information on the carcinogenic potential of chemicals is only availably for High Production Volume products. There is however, a pressing need for alternative methods allowing for the chronic toxicity of substances, including carcinogenicity, to be detected earlier and more reliably. He...

ORGANISM(S): Mus musculus

2010-10-02 | E-GEOD-22180 | biostudies-arrayexpress

Genome-wide RING1B binding in Fbxl10 overexpressing 3T3-L1 cells at day 2 of differentiation

We analyzed RING1B binding regions in 3T3-L1 cell lines transduced with the retroviral vector for V5-tagged Fbxl10 or its dF-box mutant. RING1B ChIP-seq in empty, Fbxl10-1, and dF-box mutant vector transduced 3T3-L1 preadipocytes, in duplicate, and V5-Fbxl10 ChIP-seq in Fbxl10 overexpressing 3T3-L1 ...

ORGANISM(S): Mus musculus

2015-03-04 | E-GEOD-64312 | biostudies-arrayexpress

RNAi knockdown of Tip60 and Usp7 in mouse 3T3-L1 adipocytes

Knockdown of Tip60 or Usp7 in differentiated 3T3-L1 adipocytes

ORGANISM(S): Mus musculus

2013-08-28 | E-TABM-1145 | biostudies-arrayexpress

Mus musculus strain:3T3-L1 cell

Transcriptome analysis of tyrosine restricted 3T3-L1 cells (pCHOP-tdTomato line) with knocking down Sf3a3

PRJDB20152 | ENA

NIH-3T3 cell line response to chemotheraputic agents.

PRJNA1090518 | ENA

Liquid chromatography coupled to high-resolution mass spectrometry metabolomics: A useful tool for investigating tumor secretome based on a three-dimensional co-culture model

Three-dimensional (3D) cell culture technologies, which more closely mimic the complex microenvironment of tissue, are being increasingly evaluated as a tool for the preclinical screening of clinically promising new molecules, and studying of tissue metabolism. Studies of metabolites released int...

2023-12-12 | MTBLS5375 | MetaboLights

Gene expression profiles of human breast cancer cell lines MCF-7, T47D and MDA-MB-231 co-cultured with 3T3-L1 adipocytes.

Obesity is a known risk factor for breast cancer. To identify genes and underlying pathways in human breast cancer cells affected by interaction with mature adipocytes, two estrogen-receptor positive (ER+) breast cancer cell lines, MCF-7 and T47D, and the triple-negative (TN) breast cancer cell line...

ORGANISM(S): Homo sapiens

2018-06-22 | E-MTAB-6855 | biostudies-arrayexpress

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