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TranscriptomicsMolecular Adaptations of Striatal Spiny Projection Neurons During Levodopa-Induced Dyskinesia
L-3,4-dihydroxyphenylalanine (levodopa) treatment is the major pharmacotherapy for Parkinson's disease. However, almost all patients receiving levodopa eventually develop debilitating involuntary movements (dyskinesia). While it is known that striatal spiny projection neurons (SPNs) are involved in ...
ORGANISM(S): Mus musculus 
2014-03-03 | E-GEOD-55096 | biostudies-arrayexpress
TranscriptomicsCandida albicans DOPA-grown cells
The fungal pathogen Candida albicans produces dark-pigmented melanin when grown in a basal medium containing 1 mM l-DOPA as melanin substrate. In the widely used C. albicans strain SC5314, melanin appeared after 3-4 days of incubation in l-DOPA medium. The experiment was designed to reveal cadidat...
ORGANISM(S): Candida albicans 
2010-07-07 | E-GEOD-20338 | biostudies-arrayexpress
ProteomicsDOPA formation on tyrosine Y150 of Ribonucleotide reductase QSK R2e variant from Gardnerella vaginalis.
With a crystal structure and mass spectrometry on recombinantly expressed and purified Ribonucleotide reductase QSK R2e variant from Gardnerella vaginalis we show that this protein has a modified DOPA (3,4-Dihydroxy-L-phenylalanine) in the active site analogous to what was observed for the VPK varia...
ORGANISM(S): Gardnerella vaginalis 
2023-09-08 | PXD045227 | Pride
Qexactive hf 3 Ptm Gardnerella vaginalis 4-dihydroxyphenylalanine Tyrosine Ribonuclotide reductase Dopa 
ProteomicsAnalysis of DOPA in rat tendon type I collagen
Analysis of DOPA in the alpha 2 chain of type I collagen from rat tendon
ORGANISM(S): Rattus Norvegicus (ncbitaxon:10116) 
2020-03-03 | MSV000085052 | MassIVE
UnknownDihydroxyphenylalanine-conjugated high molecular weight polyethylenimine for targeted delivery of Plasmid.
Not available
S-EPMC11375003 | biostudies-literature
GenomicsDynamic DNA Methylation Regulates Levodopa-Induced Dyskinesia
Levodopa-induced dyskinesia (LID) is a persistent behavioral sensitization that develops after repeated levodopa (L-DOPA) exposure in Parkinson disease (PD) patients. we used reduced representation bisulfite sequencing to determine the methylation status of cytosines genome wide at base pair resolu...
ORGANISM(S): Rattus norvegicus 
2016-06-16 | E-GEOD-83385 | biostudies-arrayexpress
UnknownOral levodopa rescues retinal morphology and visual function in a murine model of human albinism.
Not available
S-EPMC6766973 | biostudies-literature
ProteomicsFactor H and related proteins in AMD
Age-related macular degeneration (AMD) is a common form of adult blindness. Risk of developing AMD is strongly linked to genetics, in particular at the Regulators of Complement Activation (RCA) locus on Chr1, which contains 6 genes, Complement Factor H (CFH) and Complement Factor H-related 1-5 (CFHR...
ORGANISM(S): Homo Sapiens 
2022-01-18 | PXD023466 | panorama
UnknownAmino Acid-Coupled Bromophenols and a Sulfated Dimethylsulfonium Lanosol from the Red Alga Vertebrata lanosa.
Not available
S-EPMC9322897 | biostudies-literature
UnknownSlow-Binding Inhibition of Tyrosinase by Ecklonia cava Phlorotannins.
Not available
S-EPMC6627058 | biostudies-literature
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