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TranscriptomicsGene expression profiling of MCF-7 cells treated with 6-shogaol
A total of 18 genes were up-regulated and 11 genes were down-regulated > 2-fold following 6-shogaol treatment Microarray experiments were performed in duplicate as follows: MCF-7 cells were treated with 10 uM of 6-shogaol or control vehicle (0.1% DMSO) for 48 h. Total RNA from cells was extracted us...
ORGANISM(S): Homo sapiens 
2012-09-01 | E-GEOD-36973 | biostudies-arrayexpress
Proteomics6-Shogaol Inhibits Oxidative Stress-induced Rat Vascular Smooth Muscle Cell Apoptosis by Regulating OXR1-p53 axis
Apoptosis of vascular smooth muscle cells (VSMCs) is closely related to the pathogenesis of cardiovascular disease, and oxidative stress is an important cause for VSMCs death. Inhibiting VSMCs apoptosis is an effective preventive strategy in slowing down the development of cardiovascular disease, es...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-22 | PXD015127 | Pride
Lc-msms Rat Vascular smooth muscle cell 6-shogaol 
TranscriptomicsGene expression analysis of IL-17 induced mice small intestinal smooth muscle strips with or without 6-shogaol.
The etiology of post-inflammatory gastrointestinal (GI) motility dysfunction, after resolution of acute symptoms of inflammatory bowel diseases (IBD) and intestinal infection, is largely unknown. Here, using an established mouse model of experimental enteritis, we show that enhancement of smooth mus...
ORGANISM(S): Mus musculus 
2012-09-15 | E-GEOD-39573 | biostudies-arrayexpress
GenomicsTranscriptional Effects of 6-Shogaol and 6-Gingerol in LPS-Stimulated BV2 Microglial Cells
Transcriptional Effects of 6-Shogaol and 6-Gingerol in LPS-Stimulated BV2 Microglial Cells
PRJNA1481526 | ENA
GenomicsAntibiofilm and antivirulence activities of 6-gingerol and 6-shogaol against Candida albicans due to hyphal inhibition
Antibiofilm and antivirulence activities of 6-gingerol and 6-shogaol against Candida albicans due to hyphal inhibition
PRJNA481457 | ENA
TranscriptomicsTranscriptional Effects of 6-Shogaol and 6-Gingerol in LPS-Stimulated BV2 Microglial Cells
This study investigated the transcriptomic effects of the ginger-derived compounds 6-Shogaol and 6-Gingerol on inflammation-associated gene expression in LPS-stimulated BV2 mouse microglial cells. RNA-seq was performed to compare gene expression profiles among untreated control cells, LPS-treated ce...
ORGANISM(S): Mus musculus 
2026-06-25 | GSE336398 | GEO
GenomicsInvestigation of anti-cancer effects of 6-shogaol on glioma through analysis of transcriptome and experimental verification
Investigation of anti-cancer effects of 6-shogaol on glioma through analysis of transcriptome and experimental verification
PRJNA887687 | ENA
TranscriptomicsAntibiofilm and antivirulence activities of 6-gingerol and 6-shogaol against Candida albicans due to hyphal inhibition
Candida albicans is an opportunistic pathogen and responsible for candidiasis. C. albicans readily forms biofilms on various biotic and abiotic surfaces, and these biofilms can cause local and systemic infections. C. albicans biofilms are more resistant than its free yeast to antifungal agents and l...
ORGANISM(S): Candida albicans 
2018-12-25 | GSE117201 | GEO
TranscriptomicsInvestigation of anti-cancer effects of 6-shogaol on glioma through analysis of transcriptome and experimental verification
Glioma is one of the most fatal and complex cancer types. Patients have poor prognosis due to aggressive disease progression or tumor recurrence, resulting in poor survival. Ginger (Zingiber officinale Roscoe) is extensively regarded as a traditional Chinese herbal medicine or condiment in cooking i...
ORGANISM(S): Homo sapiens 
2025-10-01 | GSE214898 | GEO
TranscriptomicsGene expression profiling of MCF-7 cells treated with 6-shogaol
A total of 18 genes were up-regulated and 11 genes were down-regulated > 2-fold following 6-shogaol treatment
ORGANISM(S): Homo sapiens 
2012-09-01 | GSE36973 | GEO
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