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GenomicsBisulfite Sequencing Reveals that Aspergillus flavus Holds A Hollow in DNA Methylation
Aspergillus flavus first gained scientific attention for its production of aflatoxin, the most potent naturally occurring toxin and hepatocarcinogenic secondary metabolite. For several decades, The DNA methylation status of A. flavus remains to be controversial. We first applied bisulfite sequencing...
ORGANISM(S): Aspergillus flavus 
2012-03-01 | E-GEOD-32177 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of Aspergillus flavus in response to 5-azacytidine & gallic acid
Aspergillus flavus is a common saprophyte and opportunistic pathogen producing aflatoxin (AF) and many other secondary metabolites. 5-Azacytidine (5-AC), a derivative of nucleoside cytidine, is widely used for studies in epigenetics and cancer biology as an inactivator of DNA methyltransferase and i...
ORGANISM(S): Aspergillus flavus 
2013-06-15 | E-GEOD-40202 | biostudies-arrayexpress
TranscriptomicsGenotypic and Phenotypic Versatility of Aspergillus flavus during Maize Exploitation
Several are the inputs which are able to modulate mycotoxin synthesis. In particular, when a fungus receives an external stimulus reacts by activating, through a quite well-defined signal cascade, an evident switch in its lifestyle. This profound change is also due to the activation of global gene r...
ORGANISM(S): Aspergillus flavus 
2013-09-19 | E-GEOD-28163 | biostudies-arrayexpress
TranscriptomicsThe effect of temperature on Natural Antisense Transcript (NAT) expression in Aspergillus flavus
Naturally occurring Antisense Transcripts (NATs) compose an emerging group of regulatory RNAs. These regulatory elements appear in all organisms examined, but little is known about global expression of NATs in fungi. Analysis of currently available EST sequences suggests that 352 cis NATs are pres...
ORGANISM(S): Aspergillus flavus 
2010-06-21 | E-GEOD-12594 | biostudies-arrayexpress
TranscriptomicsAspergillus flavus transcriptome under different temperature conditions
To better understand the effect of temperature on mycotoxin biosynthesis, RNA-Seq technology was used to profile the Aspergillus flavus transcriptome under different temperature conditions. This approachallowed us to quantify transcript abundance for over 80% of fungal genes including 1,153 genes th...
ORGANISM(S): Aspergillus flavus 
2011-06-16 | E-GEOD-30031 | biostudies-arrayexpress
TranscriptomicsGenes Differentially Expressed by Aspergillus flavus Strains After Loss of Aflatoxin Production by Serial Transfers
Aflatoxins are carcinogenic fungal secondary metabolites. Levels of aflatoxins in agricultural commodities are stringently regulated by many countries. A cluster of genes is responsible for aflatoxin biosynthesis by Aspergillus flavus and other closely related species. Expression of the clustered af...
ORGANISM(S): Aspergillus flavus 
2010-05-26 | E-GEOD-8185 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis for high- and low-aflatoxin-yield Aspergillus flavus strains isolated from natural environments
The molecular mechanisms underlying aflatoxin production have been well-studied in strains of the fungus Aspergillus flavus (A. flavus) under artificial conditions. However, aflatoxin biosynthesis has rarely been studied in natural isolates of A. flavus strains. In the present study, tandem mass tag...
ORGANISM(S): Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167) 
2022-02-17 | PXD027517 | Pride
Natural environments Aspergillus flavus Quantification proteome Aflatoxin production 
TranscriptomicsTranscriptional changes in Aspergillus flavus-infected maize kernels
Maize kernels are susceptible to infection by the opportunistic pathogen Aspergillus flavus. Infection results in reduction of grain quality and contamination of kernels with the highly carcinogenic mycotoxin, aflatoxin. To understand host response to infection by the fungus, transcription of approx...
ORGANISM(S): Zea mays 
2014-05-14 | E-GEOD-57629 | biostudies-arrayexpress
ProteomicsComparison of the rodlet layer proteins of Aspergillus flavus and Aspergillus fumiguatus
Atomic force microscopy (AFM) imaging showed that the rodlet layer of A. fumigatus and A. flavus was different. The objective of this project was to examine the differences in the rodlet layer of these two pathogenic Aspergillus species.
ORGANISM(S): Aspergillus flavus FRR 342 Aspergillus fumigatus Af293 
2021-09-09 | PXD020592 | Pride
Roda A. fumigatus Rodlet layer A.flavus 
TranscriptomicsGene expression profile affected by Bacillus megaterium in Aspergillus flavus NRRL 3357
Aspergillus flavus is one of the major fungal molds that colonize peanut in the field and during storage. The impact to human and animal health and to economy in agriculture and commerce are significant since this mold produces the most potent natural toxins, aflatoxins, which are carcinogenic, muta...
ORGANISM(S): Aspergillus flavus 
2013-10-22 | E-GEOD-51469 | biostudies-arrayexpress
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