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ProteomicsProteomic response to cytotoxicity of methylglyoxall
Tumor glycolysis is a target for cancer chemotherapy. Methylglyoxal (MG) is a reactive metabolite formed mainly as a by-product in anaerobic glycolysis, metabolized by glyoxalase 1 (Glo1) of the glyoxalase system. MG is increased to cytotoxic levels by clinical anticancer drugs, contributing to thei...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD029315 | Pride
Methylglyoxal Cancer chemotherapy Cytotoxicity 
Transcriptomics40 IPF patients and 8 healthy controls
There is microscopic spatial and temporal heterogeneity of pathologic changes in idiopathic pulmonary fibrosis (IPF) lung tissue, which may relate to heterogeneity in pathophysiological mediators of disease and clinical progression. We measured gene expression in samples from lung biopsies or explan...
ORGANISM(S): Homo sapiens 
2014-10-14 | E-GEOD-53845 | biostudies-arrayexpress
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S-EPMC10518569 | biostudies-literature
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