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ATP-binding cassette (ABC) transporters serve a variety of physiological functions as well as play key roles in drug resistance. The genome of the human malaria parasite, Plasmodium falciparum, encodes multiple members of this family, one of which, gABCG2, is transcribed predominantly in the gametoc...
2016-09-14 | MTBLS98 | MetaboLights
Recent reports have been suggested involvement of ABC transporters in various physiological roles.To get better insight about possible involvement of vacuolar ABC transporter MLT1/orf19.5100 in different physiological roles transcriptional profiling have been peformed and compared between WT(SC5314...
ORGANISM(S): Candida albicans 
Transcriptomic Profiling of SLC and ABC Transporters in the Human Term Placenta
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC tran...
ORGANISM(S): Dictyostelium discoideum AX4 
ATP-binding cassette (ABC) transporters can translocate a broad spectrum of molecules across the cell membrane including physiological cargo and toxins. ABC transporters are known for the role they play in resistance towards anticancer agents in chemotherapy of cancer patients. There are 68 ABC tran...
ORGANISM(S): Dictyostelium discoideum AX4 
2013-06-14 | GSE45555 | GEO
ATP-binding cassette (ABC) transporters contribute to development of resistance to anti-cancer drugs via ATP-dependent drug efflux. A major goal of our study was to investigate associations between expression of ABC transporters and outcome of breast carcinoma patients. ABCA5/6/8/9/10, ABCB1/5/11, A...
ORGANISM(S): Homo sapiens 
Prokaryotes acquire essential nutrients primarily through ATP-binding cassette (ABC) importers, 18 consisting of an ATPase, a permease, and a substrate-binding protein. These importers are highly 19 underrepresented in proteomic databases, limiting our knowledge about their cellular copy numbers,20 ...
ORGANISM(S): Escherichia coli 
2025-05-26 | PXD061770 | Pride
Solute carriers (SLC) and ATP-binding cassette (ABC) transporters are essential for placental solute exchange and fetal protection, yet their transcriptomic profiles in the human placenta remain poorly characterized. Moreover, although fetal sex influences placental development and function, its imp...
ORGANISM(S): Homo sapiens 
2026-09-09 | GSE325186 | GEO
8 week-old male Hsd:ICR(CD-1) mice were fed ad libitum a standard chow (Harlan Teklad diet 2018S) and housed in groups of five. Animals were then divided into 3 pools (n=10) and sacrificed. The small intestine was extracted and divided into three sections, where the first 2-3 cm after the stomach co...
ORGANISM(S): Mus musculus 
The opportunistic yeast pathogen Candida glabrata is recognized for its ability to acquire resistance during prolonged treatment with azole antifungals. Resistance to azoles is largely mediated by the transcription factor PDR1, resulting in the upregulation of ATP-binding cassette (ABC) transporter ...
ORGANISM(S): Candida glabrata 
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