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In the activated B cell-like (ABC) subtype of diffuse large B cell lymphoma (DLBCL), NF-kappaB activity is essential for viability of the malignant cells and is sustained by constitutive activity of IkappaB kinase (IKK) in the cytoplasm. Here, we report an unexpected role for the bromodomain and ext...
ORGANISM(S): Homo sapiens 
Hippocampal tissue from pilocarpine treated mice was examined by mass spectrometry to determine the change in levels of ABC transporter proteins.
ORGANISM(S): Mus musculus (Mouse) 
2022-12-03 | PXD037454 | Pride
Age/autoimmune-associated B cells (ABCs) are a T-bet dependent B cell subset, which accumulates prematurely in autoimmune settings. The molecular pathways that regulate ABCs in autoimmunity are largely unknown. The SWEF proteins include SWAP-70 and DEF6, a newly identified SLE risk variant. SWEF-def...
ORGANISM(S): Mus musculus 
2018-03-01 | GSE99480 | GEO
Role of SWEF proteins in ABC differentiation
The opportunistic yeast pathogen Candida glabrata is recognized for its ability to acquire resistance during prolonged treatment with azole antifungals. Resistance to azoles is largely mediated by the transcription factor PDR1, resulting in the upregulation of ATP-binding cassette (ABC) transporter ...
ORGANISM(S): Candida glabrata 
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