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Functional analysis of ABCB5 in A375 and G3361 melanoma cells, by comparing stably-transfected controls to ABCB5-shRNA-targeted cells. 12 samples total. Replicates n=3 for the following 4 groups: A375 pSUPER-retro-puro-Vector vs. A375 pSUPER-retro-puro-ABCB5-KD; G3361 pSUPER-retro-puro-shCNTRL vs. G...
ORGANISM(S): Homo sapiens 
Melanoma growth is driven by malignant melanoma initiating cells (MMIC) identified by expression of the ATP-binding cassette (ABC) member, ABCB5. ABCB5+ melanoma subpopulations have been shown to overexpress the vasculogenic differentiation markers CD144 (VE-cadherin) and TIE-1 and are associated...
ORGANISM(S): Homo sapiens 
ABCB5 is marker for Limbal epithilal stem cells. A comparison between ABCB5+ versus ABCB5- cultured human limbal epithelial cells was carried out to evaluate the properties of the limbal stem cell ABCB5+ with a special focus on their role in inflammation and angiogenesis.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD041004 | Pride
Expression data from ABCB5-positive and ABCB5-negative GBM cells
We analyzed, by HTA 2.0, the GBM cell lines LN-18, LN-229, and U-87 MG after fluoresence-activated cell sorting (FACS) into ABCB5+ and ABCB5- fractions. Poor prognosis associated with glioblastoma multiforme (GBM) results from tumor resistance to therapy and high rate of recurrence. Compelling evide...
ORGANISM(S): Homo sapiens 
2020-03-05 | GSE127895 | GEO
Genome-wide expression microarray data of MCSP- and ABCB5-enriched CTCs
Single cell RNA-seq of human ABCB5-positive limbal stem cells
Functional analysis of ABCB5 in A375 and G3361 melanoma cells, by comparing stably-transfected controls to ABCB5-shRNA-targeted cells.
ORGANISM(S): Homo sapiens 
2014-06-17 | GSE38290 | GEO
Angiogenin derived from ABCB5+ mesenchymal stem cells improves diabetic wound via enhancing angiogenesis
ABCB5 is activated by MITF and b-catenin and is associated with melanoma differentiation
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