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UnknownAn in-depth evaluation of the efficacy and safety of various treatment modalities for chronic thromboembolic pulmonary hypertension: A systematic review and network meta-analysis.

Background

Chronic thromboembolic pulmonary hypertension (CTEPH) is a major risk for pulmonary hypertension with poor prognosis. Limited data is available on the optimal treatment of choice. We aimed to comprehensively assess the efficacy and safety of CTEPH targeted therapies and update the...
S-EPMC11470563 | biostudies-literature
UnknownEffect of Statin Therapy on Neurological Outcomes in Aneurysmal Subarachnoid Hemorrhage: A Meta-Analysis of 1464 Patients.

Background

Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition complicated by cerebral vasospasm and deterioration of neurological functions. Statins have been proven to reduce the incidence of vasospasm and limit the neurological deterioration with controversial data. ...
S-EPMC12376394 | biostudies-literature
UnknownAntimicrobial resistance burden pre and post-COVID-19 pandemic with mapping the multidrug resistance in Egypt: a comparative cross-sectional study.
Overuse of antibiotics during coronavirus disease 2019 (COVID-19) in an attempt to reduce COVID-19 mortality in the short term may have contributed to long-term mortality from antimicrobial resistance (AMR). The aim of this study was to evaluate the impact of the COVID-19 pandemic on AMR in Egypt an...
S-EPMC10966009 | biostudies-literature
UnknownClinicopathological characterization and prognostic implication of FOXP3 and CK19 expression in papillary thyroid carcinoma and concomitant Hashimoto's thyroiditis.
Papillary thyroid carcinoma (PTC) is considered the most prevalent thyroid malignancy. The association between Hashimoto's thyroiditis (HT) and PTC is still unclear. We aimed to examine the clinicopathological impact of immunohistochemical staining of FOXP3 and Cytokeratin 19 in PTC and concomitant ...
S-EPMC7326975 | biostudies-literature
UnknownThe efficacy and safety of coronary sinus reducer in refractory angina: a systematic review and meta-analysis.

Background

Refractory angina is a challenging medical disorder associated with continuous anginal symptoms that do not respond to medical treatments or revascularization interventions. Coronary sinus reducer (CSR) has been introduced as a promising treatment option for patients with refracto...
S-EPMC12275377 | biostudies-literature
UnknownEfficacy and safety of isotonic versus hypotonic intravenous maintenance fluids in hospitalized children: an updated systematic review and meta-analysis of randomized controlled trials.

Background

Iatrogenic hyponatremia is a common complication following intravenous maintenance fluid therapy (IV-MFT) in hospitalized children. Despite the American Academy of Pediatrics' 2018 recommendations, IV-MFT prescribing practices still vary considerably.

Objectives

This meta-a...
S-EPMC10673968 | biostudies-literature
UnknownPulmonary Function and Aerobic Capacity Responses to Equine Assisted Therapy in Adolescents with Idiopathic Scoliosis: A Randomized Controlled Trial.

Background

Idiopathic scoliosis is a common spinal malalignment that negatively impacts the respiratory system and physical conditioning in adolescents. Equine-assisted therapy comprises therapeutic horseback riding that optimizes physical performance and mobility in a range of contexts. How...
S-EPMC9252090 | biostudies-literature
ProteomicsExpression Signature and Regulatory Role of miRNAs in Hepatocellular Carcinoma-Induced Cancer Associated Fibroblasts
The study aims to assess the influence of soluble factors from HCC on MSCs and to investigate the regulatory effect of miRNAs in human adipose- MSCs (hA-MSCs) cultured in HCC microenvironment.The results suggest an interaction between tumor cells and the surrounding stromal components and provide ev...
ORGANISM(S): Homo sapiens (Human) 
2022-04-19 | PXD024418 | Pride
Human Lc-msms Hepatocellular carcinoma 
UnknownColonoscopy screening for colorectal cancer in Egypt: a nationwide cross-sectional study.

Background

Current guidelines advocate for colorectal cancer (CRC) screening in adults who are at risk by using direct visualization methods such as colonoscopy. However, in Egypt, there is a paucity of data regarding the current practice of colonoscopy screening. Moreover, more information ...
S-EPMC10809530 | biostudies-literature
UnknownKnowledge, attitude, and practice of Egyptian medical students towards healthcare workers' recommended vaccines: a nationwide cross-sectional survey.

Background

Vaccination of healthcare workers (HCWs) is pivotal in decreasing the incidence of contagious infections in hospital settings. In this study, we assessed the knowledge, attitude, and practice regarding HCWs' recommended vaccines among medical students and interns in Egypt.

Meth...

S-EPMC11323588 | biostudies-literature
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