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TranscriptomicsSmall RNA profiling in Drosophila wild-type and nbr[f02257] mutants
nbr/CG9247 gene regulates 3'end heterogeneity of a subset of miRNAs. It is not clear how broad this effect is on small RNA population. To address this, we compared small RNA population in wild-type and tmr[f02257] mutants. This approach identified more miRNAs whose 3'end heterogeneity was affected ...
ORGANISM(S): Drosophila melanogaster 
2011-11-01 | E-GEOD-32684 | biostudies-arrayexpress
TranscriptomicsAgo1 vs Ago2-IP small RNA deep-sequencing with age in Drosophila
Drosophila miRNAs show distinct change in isoform distribution pattern with age. Some miRNAs show accumulation of the short isoforms, while other miRNAs show the accumulation of the long isoforms with age. The increase of the long isoforms of some miRNAs reflects increased 2'-O-methylated miRNA isof...
ORGANISM(S): Drosophila melanogaster 
2014-01-01 | E-GEOD-52961 | biostudies-arrayexpress
Transcriptomicssmall RNA deep-sequencing with oxidation/β-elimination with age in Drosophila
Drosophila miRNAs show distinct change in isoform distribution pattern with age. Some miRNAs show accumulation of the short isoforms, while other miRNAs show the accumulation of the long isoforms with age. The increase of the long isoforms of some miRNAs reflects increased 2'-O-methylated miRNA isof...
ORGANISM(S): Drosophila melanogaster 
2014-01-01 | E-GEOD-52960 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in dorsal skin of hairless mice orally administrated collagen hydrolysate for 12 weeks
Dietary collagen hydrolysate has been conjectured to improve skin barrier function. To investigate the effect of long-term collagen hydrolysate administration on the skin, we evaluated stratum corneum water content and skin elasticity in intrinsic aged mice. Female 9-week-old hairless mice were fed ...
ORGANISM(S): Mus musculus 
2015-06-12 | E-GEOD-62649 | biostudies-arrayexpress
ProteomicsHFpEF model heart failure mouse treated with traditional herbal medicine Goreisan
In this project we aimed to investigate the effect of Goreisan (GRS, traditional herbal medicine) on HFpEF model heart failure mouse. HFpEF was induced by administration of high-fat diet (HFD)and N-nitro-L-arginine methyl ester (L-NAME), with or without GRS. Mouse heart proteome was analyzed with LC...
ORGANISM(S): Mus Musculus (mouse) 
2025-09-02 | PXD049259 | JPOST Repository
ProteomicsMudPIT analyses of the proteins co-purified with the Interactor of Little Elongation Complex ELL subunit 1 (FLAG-ICE1), WT MED26, and D2G8 NTD-mutant MED26, affinity-purified from HEK293T cell lines
Protein Complexes Purification: We generated 293FRT cell lines that stably express FLAG-tagged ICE1 (Interactor of Little Elongation Complex ELL subunit 1; KIAA0947). We extracted nuclear proteins in the presence of Benzonase to digest nucleic acids, including both DNA and RNA, and purified the lit...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-02-20 | MSV000083465 | MassIVE
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