Sort   by:  
 Page size 
MetabolomicsIntegrated multi-omics analysis of liver metabolic dysregulation in ACE2 knockout mice
This study systematically investigated the impact of ACE2 knockout (ACE2KO) on hepatic metabolic homeostasis and its molecular mechanisms, using integrated transcriptomic, proteomic, and metabolomic profiling. ACE2 deficiency exacerbates hepatic lipid accumulation, as evidenced by elevated total cho...
2025-06-23 | MTBLS12389 | MetaboLights
MetabolomicsPomegranate Peel Extract as an Inhibitor of SARS-CoV-2 Spike Binding to Human ACE2 Receptor (in vitro): A Promising Source of Novel Antiviral Drugs
Plant extracts are rich in bioactive compounds, such as polyphenols, sesquiterpenes, and triterpenes, which potentially have antiviral activities. As a consequence of the coronavirus disease 2019 pandemic, caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) virus, thousands of...
2021-10-06 | MTBLS2309 | MetaboLights
TranscriptomicsRegulation by the homologous Ace2 and Swi5 factors of Saccharomyces cerevisiae
The homologous Ace2 and Swi5 transcription factors of Saccharomyces cerevisiae have identical DNA-binding domains, and both are cell cycle regulated. There are common target genes, as well as genes activated only by Ace2 and other genes activated only by Swi5. Keywords: genetic modification RNA was ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-05-13 | E-GEOD-11380 | biostudies-arrayexpress
ProteomicsLC-MSMS of HEK 293T cells transfected with Flag-EV or Flag-ACE2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019 (COVID-19). Alongside investigation into the virology of SARS-CoV-2, understanding the host–virus dependencies are vital for the identification and rational design of effective antiviral t...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD034168 | Pride
Lc-msms Hek 293t Ace2 
ProteomicsMDM2 influences ACE2 stability and SARS-Cov2 uptake
The Angiotensin-converting enzyme 2 (ACE2) receptor is the central entry point for SARS-Cov2. Several SAR-Cov2 substrains have developed mutations in their spike protein to maximize their use of ACE2, e.g. to strengthen ACE2 binding for increased uptake or adapt to specific amino acid properties of ...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2023-09-08 | PXD040891 | Pride
Human Ubiquitination Sars-cov2 Ace2 
ProteomicsAnalysis of SARS-CoV-2 S and human ACE2 protein by LC-MS
Analysis of intact O-linked glycopeptides for SARS-Cov-2 S and human ACE2 protein by LC-MS
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2020-09-09 | PXD019940 | Pride
Sars-cov-2 s ace2 o-glycopeptide lc-ms 
ProteomicsAnalysis of SARS-CoV-2 S and human ACE2 protein by LC-MS
Analysis of deglycosylated N-linked glycopeptides for SARS-Cov-2 S and human ACE2 protein by LC-MS
ORGANISM(S): Homo sapiens (Human) Severe acute respiratory syndrome coronavirus 2 
2020-09-09 | PXD019938 | Pride
Sars-cov-2 s ace2 deglycoslyation lc-ms 
ProteomicsAnalysis of SARS-CoV-2 S and human ACE2 protein by LC-MS
Analysis of intact N-linked glycopeptides for SARS-Cov-2 S and huamn ACE2 protein by LC-MS
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2020-09-09 | PXD019937 | Pride
Sars-cov-2 s ace2 n-glycopeptide lc-ms 
TranscriptomicsRNAseq analyses in HEK293T-ACE2 cells infected with SARS-CoV-2 (VOC Delta, 24hours) vs untreated cells
In this study a gene expression (i.e., RNAseq) analysis was performed in HEK293T-ACE2 cellular model upon infection with viral particle belonging to VOC Delta (MOI: 0.026) for 24 hours in order to have a global picture of the transcriptome landscape in response to early phase of infection of SARS-Co...
ORGANISM(S): Homo sapiens 
2022-12-01 | E-MTAB-11973 | biostudies-arrayexpress
ProteomicsCirculating ACE2-expressing Extracellular Vesicles as an Innate Antiviral Response and A Decoy Therapy to Block Broad Strains of SARS-CoV-2
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)has caused the pandemic of the coronavirus induced disease 2019 (COVID-19) with 216 million cases and 4.5 million deathsas of September 2021.Thathas been exacerbated by mutated variants such as α, β, and with high infection rates and i...
ORGANISM(S): Homo Sapiens (human) 
2021-12-10 | PXD029662 | JPOST Repository
Sort   by:  
 Page size