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Suppressing the background interferences and enhancing the analyte signals are long-term goals in high performance electrospray ionization mass spectrometry (ESI-MS) analyses. We observed that performing electrospray in the presence of a concentrated acetonitrile atmosphere suppresses background int...
ORGANISM(S): Homo sapiens (Human) 
2017-01-04 | PXD005132 | Pride
Limited proteome coverage is a common challenge in plasma or serum proteomic analysis. We find that sequential precipitation of plasma by increasing concentrations of acetonitrile yields distinct subsets of proteins. Deep analysis of the original whole plasma (Plasma), the pellets of plasma precipit...
ORGANISM(S): Homo Sapiens 
(2-Benzimidazolyl)acetonitrile derivative for the highly selective la-beling 5-formyluracil and its application in genome-wide mapping in tissues
Human plasma partitioning with acetonitrile at pH 5. Crude plasma, supernatant and pellet fractions obtained after precipitation were analyzed with X!Tandem and SpectraST; assigned with PeptideProphet probabilities were then combined using InterProphet.
ORGANISM(S): Homo sapiens (Human) 
2012-12-05 | PXD000042 | Pride
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