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ProteomicsAcetylome analysis of Bordetella pertussis reveals possible targets of novel BP0960 gene-encoded lysine deacetylase
Acetylation on ε-amino groups of lysine residues (N-ε-lysine acetylation) represents an important mechanism of post-translational regulation of protein function. However, its role and extent in the whooping cough agent Bordetella pertussis remain unknown. In this study, we analyzed the acetylomes of...
ORGANISM(S): Bacteria Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2020-07-19 | PXD016384 | Pride
Acetylome Bordetella pertussis Deacetylase activity 
ProteomicsHigh intensity interval training remodels the proteome and acetylome in human skeletal muscle
Exercise is an effective strategy in the prevention and treatment of metabolic diseases. Alterations in the skeletal muscle proteome, including post-translational modifications, regulate its metabolic adaptations to exercise. Here, we examined the effect of high-intensity interval training (HIIT) on...
ORGANISM(S): Homo sapiens (Human) 
2022-06-09 | PXD023084 | Pride
Lysine acetylation Exercise Proteome Skeletal muscle Lcms 
Proteomics: The Tip60 acetylome is a hallmark of the proliferative state in Drosophila
The acetyltransferase KAT5/Tip60 is a key epigenetic regulator of transcription and the DNA damage response. In Drosophila, Tip60 functions within the DOM-A complex to acetylate histones, but its broader substrate repertoire and cellular roles remain incompletely defined. Here, we comprehensively in...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-07-16 | PXD066107 | Pride
Acetylome Drosophila Tip60 Proliferation 
ProteomicsRegulation of cellular proteome and acetylome by catalytic and non-catalytic functions of class I histone deacetylases
Project description: Taking advantage of a newly generated model system, we examined the influence of class I HDAC catalytic and non-catalytic function on the cellular proteome and acetylome. Therefore, we generated HAP1 cell lines either lacking individual class I HDACs or expressing catalytically ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-16 | PXD030164 | Pride
Acetylome Chromatin Hdac inhibitor Histone deacetylase 
ProteomicsProteome, acetylome and succinylome analysis of pCAR1-free and pCAR1-harbouring Pseudomonas putida KT2440
The impact of the conjugative plasmid pCAR1, which is involved in carbazole degradation, on the proteome, acetylome, and succinylome of host Pseudomonas putida KT2440 was investigated using a stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative analysis.
ORGANISM(S): Pseudomonas putida KT2440 
2018-09-24 | PXD007089 | Pride
Lc-msms Silac Pcar1 Pseudomonas putida kt2440 
ProteomicsProteome, acetylome and succinylome analysis of pCAR1-free and pCAR1-harbouring Pseudomonas putida KT2440 (2)
The impact of the conjugative plasmid pCAR1, which is involved in carbazole degradation, on the proteome, acetylome, and succinylome of host Pseudomonas putida KT2440 was investigated using a stable isotope labeling by amino acids in cell culture (SILAC)-based quantitative analysis.
ORGANISM(S): Pseudomonas putida KT2440 
2018-11-22 | PXD007090 | Pride
Lc-msms Silac Pcar1 Pseudomonas putida kt2440 
ProteomicsProfiling of mouse sciatic nerve acetylome
Lysine acetylation is a reversible Post-translational modification (PTM) involved in a broad array of physiological functions. Recent studies have demonstrated the involvement of protein acetylation in modulating Schwann cells' (SCs) biology and the peripheral nervous system (PNS) regeneration. Howe...
ORGANISM(S): Mus musculus (Mouse) 
2022-10-15 | PXD029611 | Pride
Acetylome Sciatic nerve Mouse Acetylation Schwann cells 
ProteomicsComprehensive Profiling of Lysine Acetylome in Baculovirus Infected Silkworm (Bombyx mori) Cells
Bombyx mori is one of the key lepidopteran model species, and is economically important for silk production and proteinaceous drug expression. Baculovirus and insect host are important natural biological models for studying host-pathogen interactions. The impact of Bombyx mori nucleopolyhedrovirus (...
ORGANISM(S): Bombyx mori (Silk moth) 
2017-11-27 | PXD008054 | Pride
Acetylome Bmnpv Proteome Bombyx mori 
ProteomicsTime-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome
The acetyltransferases CBP and p300 are multifunctional transcriptional co-activators; however, their acetylation targets, site-specific acetylation kinetics, and function in proteome regulation are incompletely understood. We combined quantitative proteomics with novel CBP/p300-specific catalytic i...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
MSV000095981 | MassIVE
UnknownExploring the yeast acetylome using functional genomics.
Not available
S-EPMC4149804 | biostudies-literature
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