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Transcriptome of lesional skin of patients suffering from Acne inversa
Transcriptome of skin from Acne inversa lesions show specific alterations compared to healthy donor skin.
ORGANISM(S): Homo sapiens 
2020-11-03 | GSE122592 | GEO
Hidradenitis suppurativa (HS), also termed acne inversa, is a persistent inflammatory dermatological condition affecting approximately 1% of the global population, causing significant morbidity. The etiology of HS is not fully elucidated, but it is known that immune dysfunction plays a critical role...
ORGANISM(S): Homo sapiens 
To acquire a better understanding of the molecular pathogenesis of hidradenitis suppurativa (HS), we performed mRNA microarray studies to compare whole blood gene expression of HS patients to that of healthy normal subjects. No significant difference was observed in whole blood mRNA expression betwe...
ORGANISM(S): Homo sapiens 
The underlying pathogenetic factors generating the innate immune signal necessary for T cell activation, initiation and chronification of Hidradenitis suppurativa (HS, also known as Acne inversa) are still poorly understood. Emerging evidence suggests that defective keratinocyte function critically ...
miRNA expression signatures of acne inversa (AI) patients with NCSTN mutations and healthy individuals
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