Actin remodeling

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Organisms

Homo sapiens (71)
Mus musculus (68)
Drosophila melanogaster (9)
Saccharomyces cerevisiae (7)
Arabidopsis thaliana (6)
Rattus norvegicus (5)
Danio rerio (2)
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Nicotiana tabacum (1)
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Repository

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Technology Type

Mass Spectrometry (52)
Shotgun proteomics (18)
Affinity purification coupled with mass spectrometry proteomics (12)
Bottom-up proteomics (8)
Data-dependent acquisition (8)
Mass spectrometry (6)
Top-down proteomics (6)
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Instrument Platform

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NA (1)
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Publication Date

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2015 (48)
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2020 (26)
2011 (26)
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2016 (21)
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UNIPROT ID/AC

1433E_SHEEP (6)
1433Z_SHEEP (6)
6PGD_SHEEP (6)
A1AT_SHEEP (6)
A8DR93_SHEEP (6)
AL1A1_SHEEP (6)
ALBU_SHEEP (6)
ANT3_SHEEP (6)
ANXA2_SHEEP (6)
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PDXK_SHEEP (6)
PLMN_SHEEP (6)
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W5NPN4_SHEEP (6)
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W5NUN8_SHEEP (6)
W5NUX8_SHEEP (6)
W5NVC9_SHEEP (6)
W5NXN2_SHEEP (6)
W5NY95_SHEEP (6)
W5NYA7_SHEEP (6)
W5P1X9_SHEEP (6)

CHEBI ID

CHEBI:30769 (3)
CHEBI:16708 (2)
CHEBI:13389 (2)
CHEBI:26806 (2)
CHEBI:17050 (2)
CHEBI:17659 (2)
CHEBI:16908 (2)
CHEBI:16015 (2)
CHEBI:16235 (2)
CHEBI:17552 (2)
CHEBI:15422 (2)
CHEBI:16761 (2)
CHEBI:16027 (2)
CHEBI:17895 (2)
CHEBI:17368 (2)
CHEBI:143106 (1)
CHEBI:81810 (1)
CHEBI:58027 (1)
CHEBI:166563 (1)
CHEBI:139445 (1)
CHEBI:41094 (1)
CHEBI:57865 (1)
CHEBI:60377 (1)
CHEBI:58477 (1)
CHEBI:456215 (1)
CHEBI:29988 (1)
CHEBI:29993 (1)
CHEBI:167860 (1)
CHEBI:167740 (1)
CHEBI:183489 (1)

Metabolite Name

Uracil (3)
D-Glucose 6-phosphate (3)
Citrate (3)
Uridine 5'-diphosphoglucuronic acid (2)
L-Glutathione (reduced) (2)
N-Acetyl-1-aspartylglutamic acid (2)
Cytidine 5'-diphosphocholine (2)
Cholecalciferol (2)
L-Glutathione oxidized (2)
Vincristine (2)
N-Acetylglucosamine 1-phosphate (2)
6-Acetylmorphine (2)
S-Lactoylglutathione (2)
S-Adenosylmethionine (2)
Malate (2)
L-Cystine (2)
UDP (2)
3-phosphoglycerate (2)
NAD+ (2)
AMP (2)
ATP (2)
Valine (2)
Thymine (2)
Thiamine (2)
Cytarabine (2)
Purine (2)
Methyldopa (2)
Adenosine 5'-monophosphate (2)
DL-Tryptophan (2)
N-Acetylneuraminic acid (2)

First Public Date

2026 (43)
2025 (22)
2024 (20)
2014 (20)
2023 (19)
2022 (18)
2020 (15)
2019 (15)
2021 (7)
2015 (7)
2018 (5)
2013 (3)
2017 (2)
2016 (1)

Classification

protozoa (2)

Study type

Transcription profiling by array (112)
RNA-seq of coding RNA (34)
ChIP-seq (24)
Methylation profiling by array (11)
Unknown experiment type (7)
RNA-seq of coding RNA from single cells (5)
ChIP-chip by tiling array (4)
ChIP-chip by array (3)
Transcription profiling by RT-PCR (2)
Single nucleus RNA sequencing (2)
RNA-seq of non coding RNA (2)
MeDIP-seq (1)
MicroRNA profiling by high-throughput sequencing (1)
Cell line - High-throughput sequencing (1)
MicroRNA profiling by high throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)
ATAC-seq (1)
RIP-seq (1)
ScATAC-seq (1)
DNA-seq (1)
Methylation profiling by high throughput sequencing (1)

Release Date

2025 (206)
2022 (192)
2021 (182)
2023 (175)
2020 (153)
2024 (140)
2015 (139)
2019 (137)
2014 (126)
2018 (123)
2016 (114)
2017 (113)
2013 (94)
2012 (75)
2010 (72)
2011 (70)
2009 (57)
2008 (50)
2026 (39)
2007 (31)
2006 (23)
2005 (13)
2002 (8)
2000 (8)
2004 (4)
2003 (4)
2001 (4)
1999 (4)
1998 (1)

Lab affiliation

Cancer Biology Department, Fox Chase Cancer Center, Philadelphia, PA, USA (3)
Academia Sinica, Institute of Biological Chemistry (1)
Associate Professor, University of Nevada, Reno department of Pharmacology (1)
Binzhou Medical University (1)
Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research and Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands (1)
Bowling Green State University (1)
Cancer Biology Program, Fox Chase Cancer Center, Philadelphia, PA, USA (1)
Cell Biology, Neurobiology and Biophysics, Department of Biology, Faculty of Science, Utrecht University, Padualaan, Utrecht, 3584 CS, The Netherlands (1)
Cell Structure Laboratory, National Center for Biotechnology (CNB-CSIC) (1)
Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, Australia (1)
Chair of Biochemistry II, Theodor Boveri-Institute, Biocenter, University of Würzburg, Würzburg, Germany (1)
Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang 310052, China (1)
Core Facility for Omics Sciences, IRCCS Istituto Giannina Gaslini, Genoa, Italy (1)
Department of Cellular & Molecular Physiology Milton S. Hershey Medical Center Penn State College of Medicine Hershey, PA, USA (1)
Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea (1)
Department of Medicine, Columbia University Irving Medical Center (1)
Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts, USA (1)
Department of Pathology, University of North Carolina at Chapel Hill (1)
Department of Pediatrics, Department of Cell Biology, Neurobiology and Anatomy Medical College of Wisconsin, Milwaukee, WI, United States (1)
Department of Pharmacology, Physiology & Neuroscience School of Medicine University of South Carolina Columbia, South Carolina, 29209 USA (1)
Department of Physiological Sciences, Faculty of Medicine and Health Sciences, University of Barcelona and IDIBELL, Barcelona (Spain) Phone: +34 93 402 90 88 (1)
Department of Plant Biology, Uppsala BioCenter, Swedish University of Agricultural Sciences and Linnean Center for Plant Biology, Uppsala, Sweden Department of Biology, University of Crete, Heraklion, Greece Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, Heraklion, Greece (1)
Department of Virology and Viral Animal Diseases, National Veterinary Research Institute - State Research Institute, Pulawy, Poland (1)
Division Proteomics of Stem Cells and Cancer (B230), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 581, 69120 Heidelberg, Germany (1)
Dominick P. Purpura Department of Neuroscience, Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY, 10461, USA (1)
EDyP (1)
Gannan Normal University (1)
Gene Expression and Muscular Dystrophy Unit, Division of Genetics and Cell Biology, IRCCS San Raffaele Scientific Institute, Milan, Italy (1)
IRCCS IST. G. Gaslini (1)
Inner Mongolia Key Laboratory of Equus Science Research and Technology Innovation, Inner Mongolia Agricultural University (1)

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TFAM loss induces nuclear actin assembly upon mDia2 malonylation to promote liver cancer metastasis

The mechanisms underlying cancer metastasis remain poorly understood. Here, we report that TFAM deficiency rapidly and stably induced spontaneous lung metastasis in mice with liver cancer. Interestingly, unexpected polymerization of nuclear actin was observed in TFAM-knockdown HCC cells when cytoske...

2022-06-23 | MTBLS4307 | MetaboLights

The nuclear actin-related protein Arp6 contributes to the radial positioning of chromosome territories.

The chromatin of individual chromosomes is organized into chromosome territories (CTs) in the interphase nucleus. The spatial arrangement of CTs is non-random and evolutionarily conserved. The gene-dense and gene-poor CTs are positioned in the nuclear center and periphery, respectively. As candidate...

ORGANISM(S): Gallus gallus

2015-11-04 | E-GEOD-14220 | biostudies-arrayexpress

Transcription profiling of human dendritic cells from PLOSL patients show abnormalities in pathways of actin bundling and immune response

This study was aimed to identify pathways associated with loss-of-function of the DAP12/TREM2 receptor complex and thus gain insight into pathogenesis of PLOSL (polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy). Transcript profiles of PLOSL patients' DCs showed differenti...

ORGANISM(S): Homo sapiens

2008-11-06 | E-GEOD-3624 | biostudies-arrayexpress

Novel Roles fro ERK5 and Cofiin as Critical Mediators Linking Estrogen Receptor α-Driven Transcription, Actin Reorganization and Invasiveness in Breast cancer

Cancer cell motility and invasiveness are fundamental characteristics of the malignant phenotype and are regulated through diverse signaling networks involving kinases and transcription factors. In this study, we identify a nuclear hormone receptor (ERα)-protein kinase (ERK5)-cofilin (CFL1) network ...

ORGANISM(S): Homo sapiens

2014-06-03 | E-GEOD-53394 | biostudies-arrayexpress

KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma [RNA-seq]

PRJNA1020789 | ENA

Actin dependent astrocytic infiltration is a key step for axon defasciculation during remodeling

PRJNA788369 | ENA

KLF5 regulates actin remodeling to enhance the metastasis of nasopharyngeal carcinoma [ChIP-seq]

PRJNA1020788 | ENA

Comparative transcriptome analysis of DFAT cells after the treatment with Y-27632 and the transfection of Mkl1 siRNA

Cellular differentiation is regulated through activation and repression of defined transcription factors. A hallmark of differentiation is a pronounced change in cell shape, which is determined by dynamics of the actin cytoskeleton. In de-differentiated fat (DFAT) cells and 3T3-L1 cells, we showed t...

ORGANISM(S): Mus musculus

2014-03-28 | E-GEOD-52334 | biostudies-arrayexpress

Distribution of Arp4 in G2/M phase

The actin-related proteins (ARPs) comprise a conserved protein family. Arp4p is found in large multisubunits of the INO80 and SWR1 chromatin remodeling complexes and in the NuA4 histone acetyltransferase complex. Here we show that arp4 (arp4S23AD159A) temperature-sensitive cells are defective in G2/...

ORGANISM(S): Saccharomyces cerevisiae

2010-06-11 | E-GEOD-7276 | biostudies-arrayexpress

Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion

PRJNA679071 | ENA

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