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ProteomicsInvestigating the monomer-dimer transition of PKD1 kinase domain with EDC crosslinking
The project aim was to generate experimental constraints for the in silico modeling of the dimeric structure of the PKD kinase domain. And identify conformational changes upon dimerization. For this we used the heterobifunctional zero length crosslinker EDC to identify salt bridges within the protei...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031997 | Pride
Protein kinase d Kinase domain dimer Activation loop ordering 
UnknownStructural basis of human p70 ribosomal S6 kinase-1 regulation by activation loop phosphorylation.
Not available
S-EPMC2836063 | biostudies-literature
UnknownDisorder-to-Order Transition of an Active-Site Loop Mediates the Allosteric Activation of Sortase A.
Not available
S-EPMC4624160 | biostudies-literature
UnknownCa2+ binding induced sequential allosteric activation of sortase A: An example for ion-triggered conformational selection.
Not available
S-EPMC6188747 | biostudies-literature
UnknownStructural Basis for the Activation and Target Site Specificity of CDC7 Kinase.
Not available
S-EPMC7416108 | biostudies-literature
UnknownQuantitative reconstitution of mitotic CDK1 activation in somatic cell extracts.
Not available
S-EPMC2882237 | biostudies-literature
UnknownMolecular mechanisms of human IRE1 activation through dimerization and ligand binding.
Not available
S-EPMC4536996 | biostudies-literature
UnknownMolecular basis of thrombomodulin activation of slow thrombin.
Not available
S-EPMC2844540 | biostudies-literature
UnknownNovel insights into the modulation of the voltage-gated potassium channel K<sub>V</sub>1.3 activation gating by membrane ceramides.
Not available
S-EPMC11367112 | biostudies-literature
UnknownStructural basis for selective small molecule kinase inhibition of activated c-Met.
Not available
S-EPMC3064177 | biostudies-literature
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