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TranscriptomicsTranscriptome and translatome profiling of CPX 90m effects in neuroblastoma cells CHP134
Neuroblastoma (NB) is the most frequent extracranial solid tumour of childhood. Clinical courses are highly variable, ranging from spontaneous regression/maturation to rapid progression despite intensive multimodal therapy. The estimation of 5-year event free survival in high-risk patients of only a...
ORGANISM(S): Homo sapiens 
2015-02-04 | E-GEOD-60675 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling in Engrailed2 knockout mice reveals common molecular pathways associated with ASD.
Background: Transcriptome analysis has been used in autism spectrum disorder (ASD) to unravel common pathogenic pathways based on the assumption that distinct rare genetic variants or epigenetic modifications affect common biological pathways dysregulated in ASD. To unravel recurrent ASD-related neu...
ORGANISM(S): Mus musculus 
2013-12-23 | E-GEOD-51612 | biostudies-arrayexpress
TranscriptomicsTranslatome and transcriptome profiling of SH-SY5Y cells treated with sublytic doses of staphylococcal alpha-hemolysin
Genome-wide analysis of translation has the potential to provide major contributions in understanding the pathophysiology of infection processes, given the complex interplay between pathogens and host cells. Informations about the translational state of mRNAs or the activity of RNA binding proteins ...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-50652 | biostudies-arrayexpress
TranscriptomicsTranslatome and transcriptome profiling of FK866 response in Jurkat cells
We treated Jurkat cells for 48 hr with a sublethal dose of FK866 (5 nM) and DMSO (Mock, control treatment). RNA samples for microarrays derived from fractionated samples by sucrose gradient (sub-polysomes, polysomes), giving us the chance to perform an analysis among polysomal/subpolysomal distribu...
ORGANISM(S): Homo sapiens 
2015-04-01 | E-GEOD-53772 | biostudies-arrayexpress
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