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ProteomicspNPs N-terminomics - Determination of the substrate repertoire of ADAMTS2, 3, and 14 significantly broadens their functions and identifies extracellular matrix organization and TGF-β signaling as primary targets
N-terminomics (iTRAQ-TAILS) applied to the ADAMTS2, 3 and 14.
ORGANISM(S): Homo sapiens (Human) 
2016-01-12 | PXD002354 | Pride
Adamts14 Adamts2 Adamts3 
ProteomicsTAILS on mouse skin deficient for ADAMTS2 and ADAMTS14
TAILS 4-Plex on mouse skin. 114 - WT; 115 - ADAMTS2-KO; 116 - ADAMTS14-KO; 117 - ADAMTS2TS14-double KO.
ORGANISM(S): Mus musculus (Mouse) 
2021-04-16 | PXD022179 | Pride
Adamts Mouse Skin Procollagen n-proteinase Tails 
GenomicsA Patient-Analog Adamts2 Knock-In Murine Model Reveals Fibroblast-Centered Extracellular Matrix Failure in Dermatosparaxis Ehlers–Danlos Syndrome (dEDS)
A Patient-Analog Adamts2 Knock-In Murine Model Reveals Fibroblast-Centered Extracellular Matrix Failure in Dermatosparaxis Ehlers–Danlos Syndrome (dEDS)
PRJNA1512051 | ENA
TranscriptomicsA Patient-Analog Adamts2 Knock-In Murine Model Reveals Fibroblast-Centered Extracellular Matrix Failure in Dermatosparaxis Ehlers–Danlos Syndrome (dEDS)
Dermatosparaxis Ehlers–Danlos syndrome (dEDS) is a rare autosomal recessive connective tissue disorder caused by biallelic pathogenic variants in ADAMTS2, which encodes the principal N-proteinase responsible for processing fibrillar procollagens. Although defective procollagen cleavage is a defining...
ORGANISM(S): Mus musculus 
2026-08-22 | GSE343646 | GEO
UnknownDopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics.
Not available
S-EPMC6861307 | biostudies-literature
UnknownOpposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function.
Not available
S-EPMC10953099 | biostudies-literature
UnknownADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis.
Not available
S-EPMC9089798 | biostudies-literature
UnknownIdentification of an ADAMTS2 frameshift variant in a cat family with Ehlers-Danlos syndrome.
Not available
S-EPMC10468306 | biostudies-literature
UnknownSkeletal Class III Malocclusion Is Associated with ADAMTS2 Variants and Reduced Expression in a Familial Case.
Not available
S-EPMC9505033 | biostudies-literature
UnknownGene expression profiling of craniofacial fibrous dysplasia reveals ADAMTS2 overexpression as a potential marker.
Not available
S-EPMC4314047 | biostudies-literature
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