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K562 cells (duplicate cultures A & B) are treated with 50 micromolar hemin for 0, 6, 12, 24, 48, 72 hours followed by RNA extraction and gene expression profiling on Affymetrix human U133A arrays and analysis by MAS 5.0
ORGANISM(S): Homo sapiens 
computational analysis of transcriptomic information during erythroid development Experiment Overall Design: mRNA expression profiling was used to characterize developing erythroid cells at 6 time points during differentiation.
ORGANISM(S): Homo sapiens 
BAF57, a component of the SWI/SNF chromatin remodeling complex conglomerate,modulates androgen receptor activity to promote prostate cancer. However the molecular consequences of tumor associated BAF57 elevation have remianed undefined in advanced disease such as castration resistant prostate cance...
ORGANISM(S): Homo sapiens 
Identification of the molecular changes that promote viability and metastatic behaviour of prostate cancer cells is critical for the development of improved therapeutic interventions for prostate cancer. Stat5a/b and Stat3 are both constitutively active in locally-confined and advanced prostate canc...
ORGANISM(S): Homo sapiens 
Energy Substrate Uptake and Metabolism are Preserved in Hypertrophic Caveolin-3 Knockout Hearts Experiment Overall Design: 3 wild types, 3 knockouts
ORGANISM(S): Mus musculus 
Retinoids have been used as potential chemotherapeutic or chemo-preventive agents because of their differentiation, anti-proliferative, pro-apoptotic, and anti-oxidant effects. We investigated the effect of all trans- retinoic acid (ATRA) at different stages of the neoplastic transformation using an...
ORGANISM(S): Homo sapiens 
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