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Adhikari et al Proteomics data supporting "Development of a Covalent Inhibitor of Gut Bacterial Bile Salt Hydrolases"
ORGANISM(S): Bifidobacterium Adolescentis (ncbitaxon:1680) Homo Sapiens (ncbitaxon:9606) 
2019-10-23 | MSV000084491 | MassIVE
Targeted protein degradation (TPD) has emerged as a powerful approach for removing (rather than inhibiting) proteins implicated in diseases. A key step in TPD is the formation of an induced proximity complex where a degrader molecule recruits an E3 ligase to the protein of interest (POI), facilitat...
ORGANISM(S): Homo sapiens (Human) 
2022-10-01 | PXD033763 | Pride
The oncogenic kinase AURORA A is essential for mitotic progression, and its catalytic inhibition arrests cells at the G2/M-transition. Unexpectedly, partial degradation of AURORA A by PROTACs (proteolysis targeting chimeras) induces profound S-phase defects, revealing a non-catalytic scaffolding fun...
ORGANISM(S): Homo sapiens (Human) 
2026-06-03 | PXD069843 | Pride
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