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MetabolomicsRegional HNSCC metabolomics reveals widespread changes to one-carbon metabolism and S-adenosylmethionine metabolism across tumour core, tumour edge and adjacent non-tumour tissues

Cancer, including head and neck squamous cell carcinoma (HNSCC), induces changes to metabolism that drive the disease. Regional metabolomics can help to understand metabolic variation across the tumour including changes near the tumour core, where hypoxia is likely more pronounced. We apply ultra...

2026-06-03 | MTBLS1905 | MetaboLights
MetabolomicsMetabolomics and 16S rRNA sequencing of human colorectal cancers and adjacent mucosa
Not available
ORGANISM(S): Homo sapiens 
ST001087 | MetabolomicsWorkbench
ProteomicsHuman osteosarcoma and adjacent normal tissues
Osteosarcoma is the most common primary bone cancer in children, adolescents and young adults. It is a rare cancer type. To obtain a comprehensive view of protein expression in osteosarcoma, quantitative TMT–MS was performed with six pairs of osteosarcoma specimens and adjacent normal tissue.
ORGANISM(S): Homo sapiens (Human) 
2025-05-13 | PXD038452 | Pride
Human Osteosarcoma Tmt-ms 
GenomicsHuman adjacent normal colon downsampled related to GSE158636
Human adjacent normal colon downsampled related to GSE158636
PRJNA700434 | ENA
GenomicsHuman bladder cancer tissues: tumor VS adjacent normal
Human bladder cancer tissues: tumor VS adjacent normal
PRJNA952237 | ENA
ProteomicsA comparative quantitative LC-MS/MS profiling analysis of human pancreatic adenocarcinoma, adjacent-normal tissue, and patient-derived tumour xenografts
This study describes the comparative quantitative LC-MS/MS proteomic analysis of the membrane-enriched proteome of 10 human pancreatic ductal adenocarcinomas, 9 matched adjacent-normal pancreas and patient derived xenografts (PDX) in mice (10 at F1 generation and 10 F2).
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-01-17 | PXD010841 | Pride
Pancreatic cancer Mass spectrometry Lc-ms/ms 
GenomicsColonic adenoma and adjacent normal single-cell RNA-seq
Colonic adenoma and adjacent normal single-cell RNA-seq
PRJNA482649 | ENA
TranscriptomicsGenomic profiling reveals unique molecular alterations in hepatoblastomas and adjacent hepatocellular carcinomas in B3C3F1 mice
The cell of origin of hepatoblastoma in humans and mice (HB) is unknown; it has been hypothesized to be a transformed hepatocyte, an oval cell, or a multipotent hepatic progenitor cell. In mice, the current dogma is that HBs arise within hepatocellular neoplasms as a result of further transformation...
ORGANISM(S): Mus musculus 
2015-09-01 | E-GEOD-67316 | biostudies-arrayexpress
TranscriptomicsGene expression data from healthy, adjacent normal and tumor colon cells
Gene expression profiles of paired normal adjacent mucosa and tumor samples from 98 individuals and 50 healthy colon mucosae, were obtained through Affymetrix Human Genome U219 Arrays. This dataset is in the context of the COLONOMICS project and to query additional information you can visit the proj...
ORGANISM(S): Homo sapiens 
2014-03-14 | E-GEOD-44076 | biostudies-arrayexpress
TranscriptomicsmiRNA expression differences between FFPE prostate cancer and adjacent normal tissues using real-time quantitative PCR array analysis
Laser Capture Microdissected cells from archival FFPE Prostate cancer and normal adjacent tissues from 10 patients (5 CA and 5 AA) were converted to cDNA and analysed by PCR array to identify differentially expressed miRNAs between the groups. Selected differentially expressed miRNAs were further va...
ORGANISM(S): Homo sapiens 
2013-11-15 | E-GEOD-48430 | biostudies-arrayexpress
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