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GenomicsADME gene variants in multiple myeloma susceptibility
ADME gene variants in multiple myeloma susceptibility
PRJNA777260 | ENA
GenomicsADME gene variants in multiple myeloma susceptibility
The metabolism of xenobiotics is regulated by phase I and II enzymes, and by transporters encoded by the absorption, distribution, metabolism, and excretion (ADME) genes. It is known that the activity of these proteins is influenced by the presence of polymorphic variants in the corresponding gene t...
ORGANISM(S): Homo sapiens 
2021-11-03 | GSE187009 | GEO
UnknownAn integrated assessment of the ADME properties of the CDK4/6 Inhibitor ribociclib utilizing preclinical in vitro, in vivo, and human ADME data.
Not available
S-EPMC7287031 | biostudies-literature
ProteomicsOCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
3D spheroids of primary human hepatocytes (3D PHH) keep a differentiated phenotype with retained metabolic function and proteome fingerprint for weeks in culture. As a result, 3D PHH are gaining ground as a model for mechanistic studies on liver homeostasis and in vitro to in vivo (IVIV)predictions...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD045733 | Pride
Human Hepatocytes Adme Liver 
UnknownADME-Space: a new tool for medicinal chemists to explore ADME properties.
Not available
S-EPMC5527008 | biostudies-literature
TranscriptomicsNASH
Non-alcoholic fatty liver disease (NAFLD) is characterized by a series of pathological changes that can progress from simple fatty liver disease to non-alcoholic steatohepatitis (NASH). The objective of this study is to describe changes in global gene expression associated with the progression of NA...
ORGANISM(S): Homo sapiens 
2011-07-12 | E-MEXP-3291 | biostudies-arrayexpress
GenomicsADME_gene_expression
Gene expression for 303 ADME and ADME related genes (averaged log2 signal intensities using Human-WG6v2 Expression BeadChip)
EGAD00010001709 | EGA
UnknownRefined ADME Profiles for ATC Drug Classes.
Not available
S-EPMC11944659 | biostudies-literature
UnknownCharacterization of ADME gene variation in 21 populations by exome sequencing.
Not available
S-EPMC5287433 | biostudies-literature
UnknownNoncoding microRNAs: small RNAs play a big role in regulation of ADME?
Not available
S-EPMC7061715 | biostudies-literature
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