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GenomicsADME gene variants in multiple myeloma susceptibility
ADME gene variants in multiple myeloma susceptibility
PRJNA777260 | ENA
GenomicsADME gene variants in multiple myeloma susceptibility
The metabolism of xenobiotics is regulated by phase I and II enzymes, and by transporters encoded by the absorption, distribution, metabolism, and excretion (ADME) genes. It is known that the activity of these proteins is influenced by the presence of polymorphic variants in the corresponding gene t...
ORGANISM(S): Homo sapiens 
2021-11-03 | GSE187009 | GEO
ProteomicsOCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids
3D spheroids of primary human hepatocytes (3D PHH) keep a differentiated phenotype with retained metabolic function and proteome fingerprint for weeks in culture. As a result, 3D PHH are gaining ground as a model for mechanistic studies on liver homeostasis and in vitro to in vivo (IVIV)predictions...
ORGANISM(S): Homo sapiens (Human) 
2024-08-10 | PXD045733 | Pride
Human Hepatocytes Adme Liver 
ProteomicsHigh-throughput analysis of ADME proteins in plasma extracellular vesicles for clinical surveillance
Clinical monitoring and prediction on drug ADME behaviors is of great essence due to the variability from individual patients. To date, pharmacogenomic approaches have allowed genotypic detection on a few metabolizing enzymes, mainly limited to cytochrome P450 polymorphisms. However, it is inadequat...
ORGANISM(S): Mus Musculus (mouse) 
2022-08-17 | PXD036086 | JPOST Repository
UnknownComparative untargeted proteomic analysis of ADME proteins and tumor antigens for tumor cell lines.
Not available
S-EPMC5925393 | biostudies-literature
UnknownSWAAT Bioinformatics Workflow for Protein Structure-Based Annotation of ADME Gene Variants.
Not available
S-EPMC8875676 | biostudies-literature
UnknownBioinformatics analysis of adhesin-binding potential and ADME/Tox profile of anti-Helicobacter pylori peptides derived from wheat germ proteins.
Not available
S-EPMC9189888 | biostudies-literature
UnknownCharacterization of preclinical radio ADME properties of ARV-471 for predicting human PK using PBPK modeling.
Not available
S-EPMC12151198 | biostudies-literature
UnknownIn Vitro ADME Properties of Two Novel Antimicrobial Peptoid-Based Compounds as Potential Agents against Canine Pyoderma.
Not available
S-EPMC6017477 | biostudies-literature
Unknown3D-QSAR, ADME-Tox, and molecular docking of semisynthetic triterpene derivatives as antibacterial and insecticide agents.
Not available
S-EPMC8941842 | biostudies-literature
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