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TranscriptomicsTranscription profiling of Macaca mulatta adrenal gland over a 24 hour period to investigate circadian regulation of gene expression
Circadian regulation of gene expression in central and peripheral tissue has been studied in mice. The biomedical implications of this findings led us to the development of a model in which to study the circadian mechanisms underlying primate physiology. The objective of this experiment has been to ...
ORGANISM(S): Macaca mulatta 
2007-10-05 | E-GEOD-2703 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in adrenal medulla after cardiac pressure overload
Transcriptom analysis of microdissect adrenal medulla after 8 weeks of cardiac pressure overload caused by transverse aortic constriction. Comparative transcriptome analysis was determined using the GeneChip Mouse Genome 430 2.0 Array (Affymetrix, Santa Clara, CA, USA). Six microarrays from microdis...
ORGANISM(S): Mus musculus 
2011-05-03 | E-GEOD-21829 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse adrenal gland samples at multiple time points after release into DD to characterise rhythmic gene expression in the adrenal gland
This study was performed to characterize the rhythmic transcriptome of the murine adrenal gland with a focus on the corticosterone synthesis pathway. Experiment Overall Design: LD entrained male animals were released into DD and from the second day on whole adrenals were prepared from 12 time points...
ORGANISM(S): Mus musculus 
2007-12-12 | E-GEOD-4238 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse adrenal gland from Wildtype and Per2Cry1 double mutant mice - time series
This SuperSeries is composed of the following subset Series:; GSE4238: rhythmic transcriptome in the murine wt adrenal; GSE4239: Transcriptome regulation in the adrenal gland of circadian clock deficient Per2Cry1 double mutant mice Experiment Overall Design: Refer to individual Series
ORGANISM(S): Mus musculus 
2008-06-20 | E-GEOD-4253 | biostudies-arrayexpress
TranscriptomicsSingle-nucleus and spatial transcriptome reveal adrenal homeostasis in normal and tumoural adrenal glands
The human adrenal glands are highly dynamic endocrine organs that are involved in the secretion of various hormones such as steroids and catecholamines. Here we present a single-nuclei and spatial transcriptomic analysis of healthy adult human adrenal glands to provide a complete adrenal gland atlas...
ORGANISM(S): Homo sapiens 
2023-01-01 | E-MTAB-12129 | biostudies-arrayexpress
TranscriptomicsAdrenal gland gene expression from adult (12-week old) hypertensive BPH and adult (12-week old) hypotensive BPL mice
The objective of the experiment is to determine the genes differentially expressed in the adrenal gland of adult (12-week) BPH and BPL mice. Adrenal glands from adult (12-week) hypertensive BPH mice (n=3) and adult (12-week) hypotensive BPL mice (n=3).
ORGANISM(S): Mus musculus 
2010-06-16 | E-GEOD-19342 | biostudies-arrayexpress
TranscriptomicsAdrenal gland gene expression from chromogranin A knockout mice (Mahapatra et al. 2005) vs. wild-type mice
The objective of the experiment is to determine the genes differentially expressed in the adrenal gland of the chromogranin A knockout mouse (Mahapatra et al., 2005). Adrenal glands from chromogranin A knockout mice (n=3) and wild-type control mice (n=3).
ORGANISM(S): Mus musculus 
2010-03-15 | E-GEOD-18304 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse adrenal gland from circadian clock deficien PerCry1 double mutant after 46 or 54h in DD
This array set was used to determine clock regulated genes in the adrenal gland that are not necessarily rhythmic but still controlled by the circadian TTL. Experiment Overall Design: LD entrained animals were released into DD and whole adrenal glands were dissected at the 46/54 h specified time poi...
ORGANISM(S): Mus musculus 
2007-12-07 | E-GEOD-4239 | biostudies-arrayexpress
TranscriptomicsGenome wide analysis of Adrenal Gland tissue from Gata6 conditional knockout versus Control Adrenal tissue
Transcription factor GATA6 is expressed in the fetal and adult adrenal cortex and has been implicated in steroidogenesis. To characterize the role of GATA6 in adrenocortical development and function, we generated mice in which Gata6 was conditionally deleted using Cre-LoxP recombination with Sf1-cre...
ORGANISM(S): Mus musculus 
2013-06-06 | E-GEOD-40398 | biostudies-arrayexpress
TranscriptomicsPACAP dependency of genes regulated in adrenal gland
We investigated the effects of PACAP knock out on the transcriptosome profile of adrenal gland. A 35,546-clone mouse cDNA microarray was used to investigate transcriptional changes Keywords: transcript identification design In the hybridization method employed, equal amounts (2-5 ug/15.5 ul) of tota...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-7405 | biostudies-arrayexpress
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